Results 71 to 80 of about 341,550 (314)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Chloride channel function is linked to epithelium-dependent airway relaxation [PDF]

open access: yes, 2001
We previously reported that substance P (SP) and ATP evoke transient, epithelium-dependent relaxation of mouse tracheal smooth muscle. Since both SP and ATP are known to evoke transepithelial Cl−secretion across epithelial monolayers, we tested the ...
Richard J. Paul   +2 more
core   +1 more source

Degradation transformations in topologically disordered solids: 4. Features of exponential kinetics

open access: yesТехнологія та конструювання в електронній апаратурі, 2005
The manifestations of exponential degradation kinetics in topologically disordered materials are analyzed. Degradation transformations are determined by a single prevailing activation energy value, regardless of the structural dispersity of the system ...
V. A. Balitskaya   +4 more
doaj  

Rapid high resolution T1 mapping as a marker of brain development: Normative ranges in key regions of interest. [PDF]

open access: yesPLoS ONE, 2018
ObjectivesWe studied in a clinical setting the age dependent T1 relaxation time as a marker of normal late brain maturation and compared it to conventional techniques, namely the apparent diffusion coefficient (ADC).Materials and methodsForty-two healthy
Sylvain Eminian   +4 more
doaj   +1 more source

OnM-functions and nonlinear relaxation methods

open access: yesBIT Numerical Mathematics, 1985
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Relaxation Studies on Power Equipment [PDF]

open access: yes, 2003
This paper describes a method of studying and modeling the dielectric relaxation for stationary power apparatus in an interconnected network to get the necessary aging indicators.
Yu, Xingzhou Y., Sivaswamy, Birlasekaran
core   +1 more source

Degradation processes in topologically disordered solids: 2. Monomolecular kinetic model

open access: yesТехнологія та конструювання в електронній апаратурі, 2004
Experimental results are considered on the time-dependent degradation of the effect of electron-induced dichroism in chalcogenide glassy semiconductors of the pseudobinary system As₂S₃–Sb₂S₃.
V. A. Balitskaya   +2 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Size Function Based Mesh Relaxation [PDF]

open access: yes, 2005
This thesis addresses the problem of relaxing a finite element mesh to more closely match a size function. The main contributions include new methods for performing size function based mesh relaxation, as well as an algorithm for measuring the ...
Howlett, John David
core   +1 more source

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