Results 51 to 60 of about 345,541 (356)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A quasi-experimental study to assess the effect of Benson’s relaxation on anxiety and depression among patients with heart failure in Jordan [PDF]

open access: yesAcute and Critical Care
Background Despite advancements in treatment, heart failure (HF) remains a leading cause of death. Anxiety and depression (A&D) are highly prevalent among patients with HF, negatively impacting their mortality, and morbidity.
Asad Allah Mohammed Aloran   +3 more
doaj   +1 more source

Effects of stress and relaxation on central pain modulation in chronic whiplash and fibromyalgia patients compared to healthy controls [PDF]

open access: yes, 2016
Background: Compelling evidence has demonstrated that impaired central pain modulation contributes to persistent pain in patients with chronic whiplash associated disorders (WAD) and fibromyalgia (FM).
Cagnie, Barbara   +6 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Prognosis and Treatment of Headaches

open access: yesPediatric Neurology Briefs, 1995
The prognosis and methods of coping with headaches were studied by telephone interview in 98 children followed for 10 years after diagnosis at the Department of Pediatrics, Dalhousie University and Children’s Hospital, Halifax, Canada.
J Gordon Millichap
doaj   +1 more source

Teaching basic relaxation procedures to psychiatric patients receiving electronconvulsive therapy : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

open access: yes, 1982
There has been no research on psychiatric patients examining the ability to remember relaxation skills whilst receiving electroconvulsive therapy.
Simons, Bruce Francis
core  

Perbandingan Efektifitas Relaksasi Autogenic dan Music Therapy terhadap Tingkat Nyeri Setelah Insersi Vaskuler Pasien yang Menjalani Hemodialisa [PDF]

open access: yes, 2019
The aim of this study was to compare the effectiveness of autogenic relaxation and music therapy to the level of pain in HD patients when insertion of vascular access.
haerani, B. (Beti)   +2 more
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Immuno Magnetic Thermosensitive Liposomes For Cancer Therapy [PDF]

open access: yes, 2019
The present work describes the encapsulation of the drug doxorubicin (DOX) in immuno paramagnetic thermosensitive liposomes. DOX is the most common chemotherapeutic agent for the treatment of a variety of carcinomas.
Alawak, Mohamad
core   +1 more source

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