Results 111 to 120 of about 20,208 (255)

Identification of Common Blood Metabolic Derangements Using Magnetic Resonance Signatures of the Pancreas and Liver

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4162-4175, May 2026.
ABSTRACT Aim To investigate whether common disturbances of glucose and lipid metabolism can be automatically identified from magnetic resonance signatures of the pancreas and liver. Methods In this proof‐of‐principle study, 100 individuals with a history of pancreatitis—a relatively homogeneous population at risk for metabolic derangements—underwent ...
Wandia Kimita, Juyeon Ko, Loren Skudder‐Hill, Xiatiguli Shamaitijiang, Yutong Liu, Maxim S. Petrov   +5 more
wiley   +1 more source

In Vivo Nanodiamond Quantum Sensing of Free Radicals in Caenorhabditis elegans Models

Advanced Science
Free radicals are believed to play a secondary role in the cell death cascade associated with various diseases. In Huntington's disease (HD), the aggregation of polyglutamine (PolyQ) not only contributes to the disease but also elevates free radical ...
Siyu Fan, Yue Zhang, Anna P. Ainslie, Renée Seinstra, Tao Zhang, Ellen Nollen, Romana Schirhagl   +6 more
doaj   +1 more source

Voxel-based relaxometry: a new approach for analysis of T2 relaxometry changes in epilepsy

NeuroImage, 2004
The measurement of the T2 relaxation time (T2 relaxometry) had been established as a reliable tool for the assessment of certain conditions such as temporal lobe epilepsy. The standard procedure for analysis of T2 data uses manually drawn regions of interest (ROIs).
Gaby S, Pell, Regula S, Briellmann, Anthony B, Waites, David F, Abbott, Graeme D, Jackson   +4 more
openaire   +2 more sources

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Relaxivity Modulation of Gd-HPDO3A-like Complexes by Introducing Polar and Protic Peripheral Groups

Molecules
In the last three decades, high-relaxivity Magnetic Resonance Imaging (MRI) contrast agents (CAs) have been intensively sought, aiming at a reduction in the clinically injected dose while maintaining the safety of the CA and obtaining the same ...
Sara Camorali, Loredana Leone, Laura Piscopo, Lorenzo Tei   +3 more
doaj   +1 more source

Controlled Clustering of Superparamagnetic Nanoparticles using Block Copolymers : Design of New Contrast Agents for Magnetic Resonance Imaging

, 2005
When polyelectrolyte-neutral block copolymers are mixed in aqueous solutions with oppositely charged species, stable complexes are found to form spontaneously. The mechanism is based on electrostatics, and on the compensation between the opposite charges.
Airiau, Marc, Berret, Jean-Francois, Gazeau, Florence, Kharrat, Delphine El, Sandre, Olivier, Schonbeck, Nicolas, Vacher, Annie   +6 more
core   +3 more sources

Evaluation of Brain Microstructural Alterations in Preschool Autism Spectrum Disorder: A Voxel‐Wise Multimodal MRI Study

Journal of Magnetic Resonance Imaging, Volume 63, Issue 4, Page 1053-1066, April 2026.
ABSTRACT Background Autism Spectrum Disorder (ASD) presents with early neurodevelopmental alterations in preschool children, yet comprehensive characterization using multimodal quantitative MRI remains limited in this age group. Purpose To investigate voxel‐wise brain microstructural differences in preschool ASD through integrated analysis of cerebral ...
Changhao Wang, Meiying Cheng, Yu Lu, Jinxia Guo, Xueyan Liu, Zhanqi Feng, Shipeng Liu, Xin Zhao   +7 more
wiley   +1 more source

Optimization of MRI Relaxometry for BMD Measurement and Its Correlation with DEXA

پزشکی بالینی ابن سینا, 2005
Introduction & Objective : The aim of this study was to optimize MRI conventional protocols for BMD(Bone Mineral Density) measurements using MRI Relaxometry in systems not facilitated with special multi echo protocols. Since, cortical and trabecular bone
Morteza Bakhtiari, Nader Riahi Alam, Mohammad Ali Oghabian, Ali Ghasemzadeh, Hosein Ghenaati, Saeed Sarkar, Bagher Larijani, Zohreh Hamidi Abarghooyi, naser Shakeri   +8 more
doaj  

Analytical Dual Flip Angle R1 Calculation Outside the Small‐Angle Regime

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2420-2428, April 2026.
ABSTRACT Purpose To evaluate a new analytical estimator for R1 and apparent proton density (A$$ A $$) from short‐TR dual flip angle data which does not rely on the small flip angle approximation and can thus be applied to a broader range of data, especially where relatively large flip angles are needed to achieve sufficient T1‐weighting for R1 ...
Luke J. Edwards, Kerrin J. Pine, Ilona Lipp, EBC consortium, Evgeniya Kirilina, Gunther Helms, Nikolaus Weiskopf, Catherine Crockford, Luke J. Edwards, Angela D. Friederici, Tobias Gräßle, Philipp Gunz, Carsten Jäger, Evgeniya Kirilina, Ilona Lipp, Kerrin Pine, Matyas Liptovszky, Nikolaus Weiskopf, Roman M. Wittig   +18 more
wiley   +1 more source

Fast T2 Mapping with Improved Accuracy Using Undersampled Spin-echo MRI and Model-based Reconstructions with a Generating Function

, 2014
A model-based reconstruction technique for accelerated T2 mapping with improved accuracy is proposed using undersampled Cartesian spin-echo MRI data. The technique employs an advanced signal model for T2 relaxation that accounts for contributions from ...
Frahm, Jens, Knoll, Florian, Petrovic, Andreas, Sumpf, Tilman J., Uecker, Martin   +4 more
core   +1 more source