Results 121 to 130 of about 17,492,579 (250)

Multiple-Unit Swellable/Erodible Delivery System for Oral Pulsatile Release: Preliminary Stability and In Vivo Evaluation

open access: yes, 2012
An oral multiple-unit pulsatile delivery system was evaluated for in vivo performance and physical stability. This system encompassed a minitablet core, an HPMC layer and an outer flexible and increasingly permeable acrylic film aimed at prolonging the ...
A. Maroni   +5 more
core   +1 more source

Heuristics for the Early/Tardy Scheduling Problem with Release Dates [PDF]

open access: yes
In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We analyse the performance of several dispatch rules, a greedy procedure and a decision theory local search ...
Rui A. F. S. Alves, Jorge M. S. Valente
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Increased release time of antibiotics from bone allografts through a novel biodegradable coating. [PDF]

open access: yesBiomed Res Int, 2014
Hornyák I   +7 more
europepmc   +1 more source

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