Results 81 to 90 of about 17,492,579 (250)
Asian Journal of Pharmaceutical Sciences, 2019 The object of the study was to develop a quick and reproducible accelerated in vitro release method to predict and deduce the function of the real time (37 °C) release for long acting PLGA microspheres.
Mingzhu Ye +8 more
doaj +1 more source
, 2014 Cationic liposome based siRNA delivery system has improved the efficiencies of siRNA. However, cationic liposomes are prone to be rapidly cleared by the reticuloendothelial system (RES).
Cheng, Qiang +11 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Real-time drug release monitoring from acoustically responsive scaffolds
Ultrasonics SonochemistryAcoustically responsive scaffolds (ARSs), composite hydrogels containing phase-shift droplets that are activated by ultrasound, enable on-demand drug delivery with spatiotemporal precision.
Sander Spiekhout +5 more
doaj +1 more source
DNN-based Software Reliability Model for Fault Prediction and Optimal Release Time Determination [PDF]
International Journal of Mathematical, Engineering and Management SciencesThe accurate prediction of both detected and corrected faults is crucial for enhancing software reliability and determining optimal release times. Traditional Software Reliability Growth Models (SRGMs) often focus on either fault detection or correction,
Shikha Dwivedi +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Enhanced virtual release advancing algorithm for real-time task scheduling
Journal of Information and Telecommunication, 2018 In real-time task scheduling, response time and time complexity are two of important requirements that draw many attentions. Virtual release advancing (VRA) [Tanaka, K. (2015, June). Virtual release advancing for earlier deadlines.
D. Duy, K. Tanaka
doaj +1 more source
, 2004 Interpenetrating polymer network (IPN) hydrogels of chitosan with N-vinylpyrrolidinone (NVP) as well as its copolymer with 2 -hydroxyethyl met hacrylate (HEMA) were synthesised through the photoinitiator - free photopolymerisation technique.
Swami, Salesh N., Ng, Loo-Teck
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2018 This paper uses a newly defined functional connectome and connectome values calculated in time domain of simulated neurotransmitter release (NTR) from an electrocorticogram (ECoG) to distinguish between conditioned and unconditioned stimuli.
You Zhai, Jian Zhai
doaj +1 more source