Results 71 to 80 of about 1,092,186 (345)

Fear of COVID-19 scale: Psychometric characteristics, reliability and validity in the Israeli population

open access: yesPsychiatry Research, 2020
Mental health clinicians worldwide have been expressing concerns regarding the broad psychological effects of the COVID-19 pandemic. Nonetheless, only a few studies have thus far evaluated the degree of fear of COVID-19, partially due to the lack of ...
Dana Tzur Bitan   +5 more
semanticscholar   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Reliability and Validity of the “Activity and Participation” Component in the Brief ICF Core Set for Chronic Obstructive Pulmonary Diseases Based on Rasch Analysis

open access: yesInternational Journal of COPD, 2020
Chengyao Guo,1,* Yingge Liu,1,* Shengyu Hao,2,* Liang Xie,2 Guiling Xiang,2 Yan Wu,1 Shanqun Li2 1Nursing Department, Zhongshan Hospital, Fudan University, Shanghai 200032, People’s Republic of China; 2Department of Pulmonary Medicine, Zhongshan ...
Guo C   +6 more
doaj  

Katz index of independence in ADL. Reliability and validity in short-term care.

open access: yesScandinavian Journal of Rehabilitation Medicine, 2020
This article deals with the Katz Index of Independence in Activities of Daily Living and presents a study of its reliability and validity carried out at a Department of Internal Medicine in Sweden. Enrolled nurses assessed independently 100 aged patients.
B. Brorsson, K. H. Asberg
semanticscholar   +1 more source

Reliability and Validity of the Readiness of Parenthood Scale [PDF]

open access: yes, 2007
Purpose:To examine the reliability and validity of the readiness of parenthood scale for adolescent males and females. The readiness of parenthood scale consists of 2 sub-scales.
SASAKI, Ayako, 佐々木, 綾子
core  

Validating task analysis for error identification: Reliability and validity of a human error prediction technique [PDF]

open access: yes, 2005
This paper reports on the theoretical and empirical developments for an error prediction methodology called task analysis for error identification (TAFEI). Other researchers have noted the need for theoretically driven approaches that are able to provide
Baber, Christopher   +4 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Validation of the Brazilian version of WHODAS 2.0 in patients on hemodialysis therapy

open access: yesFisioterapia em Movimento, 2018
Introduction: Chronic kidney disease and hemodialysis normally have an impact on the functioning. Objective: To validate the Brazilian version of the World Health Organization Disability Assessment Schedule 2.0 in individuals with chronic kidney ...
Shamyr Sulyvan Castro   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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