Results 31 to 40 of about 502,154 (257)

Validity and Reliability of the Korean Version of the Families’ Importance in Nursing Care-Pediatric Nurses’ Attitudes Instrument [PDF]

Child Health Nursing Research, 2018
Purpose: This study aimed to test the validity and reliability of the Korean version of the Families’ Importance in Nursing Care-Nurses’ Attitudes (FINC-NA) instrument developed by Saveman et al.
Jina Oh, Yae Young Kim, So Yeon Yoo, Haeryun Cho   +3 more
doaj   +1 more source

Psychometric properties of Turkish version of Dutch eating behavior questionnaire in adolescents aged between 12 and 18 years and assessment of the effect of age and gender on eating behaviours (tur)

Klinik Psikiyatri Dergisi, 2021
INTRODUCTION: Having a valid and reliable scale to detect eating disorders in adolescents is important for early diagnosis of individuals at risk of eating disorders and timely preventive interventions.
Ezgi Şen Demirdöğen, Pınar Algedik, Dilara Demirpençe   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Validez de una escala de resiliencia (RESI-M) en mujeres indígenas de México

Cadernos de Saúde Pública, 2018
Resumen: La resiliencia engloba una serie de capacidades y habilidades, las cuales son adquiridas como resultado de la interacción del individuo con su contexto, logrando superar sus propios límites de resistencia, a través de la generación de mecanismos,
Xiomara Sarahí Sanjuan-Meza, Erick Alberto Landeros-Olvera, Patricia Elizabeth Cossío-Torres   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The Reliability and Validity of the “Activity and Participation” Component in the Brief ICF Core Set for Chronic Obstructive Pulmonary Diseases Based on Rasch Analysis

International Journal of COPD, 2020
Chengyao Guo,1,* Yingge Liu,1,* Shengyu Hao,2,* Liang Xie,2 Guiling Xiang,2 Yan Wu,1 Shanqun Li2 1Nursing Department, Zhongshan Hospital, Fudan University, Shanghai 200032, People’s Republic of China; 2Department of Pulmonary Medicine, Zhongshan ...
Guo C, Liu Y, Hao S, Xie L, Xiang G, Wu Y, Li S   +6 more
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Validation of the Brazilian version of WHODAS 2.0 in patients on hemodialysis therapy

Fisioterapia em Movimento, 2018
Introduction: Chronic kidney disease and hemodialysis normally have an impact on the functioning. Objective: To validate the Brazilian version of the World Health Organization Disability Assessment Schedule 2.0 in individuals with chronic kidney ...
Shamyr Sulyvan Castro, Camila Ferreira Leite, Juliana Elisa Baldin, Marilita Falangola Accioly   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source