Results 71 to 80 of about 817,157 (293)

Validation of the Brazilian version of WHODAS 2.0 in patients on hemodialysis therapy

Fisioterapia em Movimento, 2018
Introduction: Chronic kidney disease and hemodialysis normally have an impact on the functioning. Objective: To validate the Brazilian version of the World Health Organization Disability Assessment Schedule 2.0 in individuals with chronic kidney ...
Shamyr Sulyvan Castro, Camila Ferreira Leite, Juliana Elisa Baldin, Marilita Falangola Accioly   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Validation of questionnaires for the measurement of health variables: Fundamental concepts

Medwave
In clinical practice and population health, it is common to use questionnaires to assess conditions or variables that are not directly observable. However, the construction and validation of these instruments or questionnaires are often poorly understood.
Natalia Riva, Diego Grandi, Benjamín Cruzat, Ruben Alvarado   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Validity and Reliability Study of the Smartphone Self-Efficacy Scale

, 2020
The aim of this study is to develop a valid and reliable scale named “Smartphone Self-Efficacy Scale”. The purposeof the scale is to determine the smartphone self-efficacy levels of people.
SAYIM AKTAY (8496447)
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Reliability and concurrent validity between two-dimensional and three-dimensional evaluations of knee valgus during drop jumps

Open Access Journal of Sports Medicine, 2016
Alexis Ortiz1,  Martin Rosario-Canales2,3,  Alejandro Rodríguez3, Alexie Seda3, Carla Figueroa3, Heidi L Venegas-Ríos4 1School of Physical Therapy, Texas Woman’s University, Houston, TX, 2Department of Anatomy & ...
Ortiz A, Rosario-Canales M, Rodríguez A, Seda A, Figueroa C, Venegas-Ríos HL   +5 more
doaj  

Construct reliability, convergent validity, and discriminant validity.

, 2019
Construct reliability, convergent validity, and discriminant validity.
Xiaoxiao Wang (337498), Liangjie Xu (401081), Yanping Hao (847399)   +2 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source