Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Cross cultural adaptation, reliability and validity of the Persian version of COVID-19 Preventive Measures questionnaire at the radiation therapy center in Yazd, Iran [PDF]
Background: Due to the crowds of people in radiation therapy centers and the importance of not interrupting the treatment process, preventive measures to deal with COVID-19 is one of the most important measures; therefore, this study aimed to evaluate ...
Farzan Madadizadeh +3 more
doaj
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Validity, practical utility, and reliability of the activPAL in preschool children [PDF]
<p>Purpose: With the increasing global prevalence of childhood obesity, it is important to have appropriate measurement tools for investigating factors (e.g. sedentary time) contributing to positive energy balance in early childhood. For pre-school
Paton, James +27 more
core +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Evaluating qualitative research: issues of reliability and validity
The issues that this paper considers arose from my experiences of teaching quantitative and qualitative research methods to postgraduate Masters students at my institution.
Anderson, C.
core
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Turkish Validity and Reliability of Pediatric Sleep Practices Questionnaire
Arzu SARIALIOĞLU +2 more
doaj +1 more source
The reliability and validity of the Lane Agility Test for collegiate basketball players
Agility is the ability to change body direction, or position in space. The game of basketball requires intermittent starts, stops, changes of direction, etc. Several tests have been developed to measure agility. The purpose of this study was to determine
Brown, Ashley E.
core +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source

