Results 31 to 40 of about 327,842 (293)

A small footprint couch‐top support device for image‐guided radiotherapy of heavy patients

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Patients with body weights close to or above 400 lbs present unique challenges in radiation therapy since the weight limit of most treatment couches decreases as the couch‐top extends toward the treatment gantry. The purpose of this work was to develop a small footprint couch‐top support platform to safely perform image‐guided ...
Huixiao Chen   +5 more
wiley   +1 more source

The First 50 Years of Software Reliability Engineering: A History of SRE with First Person Accounts [PDF]

open access: yes, 2019
Software Reliability has just passed the 50-year milestone as a technical discipline along with Software Engineering. This paper traces the roots of Software Reliability Engineering (SRE) from its pre-software history to the beginnings of the field with the first software reliability model in 1967 through its maturation in the 1980s to the current ...
arxiv   +1 more source

Investigating the Reliability in Three RAID Storage Models and Effect of Ordering Replicas on Disks [PDF]

open access: yesarXiv, 2021
One of the most important parts of cloud computing is storage devices, and Redundant Array of Independent Disks (RAID) systems are well known and frequently used storage devices. With the increasing production of data in cloud environments, we need high-reliable storage, given the importance of data.
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Multi-Stress Equivalent Optimum Design for Ramp-Stress Accelerated Life Test Plans Based on D-Efficiency

open access: yesIEEE Access, 2017
Due to time and cost limitations, multi-stress accelerated life tests (ALTs) have been gradually applied in the fields of experimental design and reliability estimation for highly reliable and long-life products.
Yunxia Chen, Wenbin Sun, Dan Xu
doaj   +1 more source

An Analysis of Factors Affecting Agricultural Tractors’ Reliability Using Random Survival Forests Based on Warranty Data

open access: yesIEEE Access, 2022
Warranty data are a valuable and easily accessible data source for manufacturers to assess the reliability of products in the field. Knowledge about the relationships between products’ reliability and reliability factors is beneficial for ...
Zhi-Lin Zhao, Heng-Jie Yu, Fang Cheng
doaj   +1 more source

Statistical Perspectives on Reliability of Artificial Intelligence Systems [PDF]

open access: yesarXiv, 2021
Artificial intelligence (AI) systems have become increasingly popular in many areas. Nevertheless, AI technologies are still in their developing stages, and many issues need to be addressed. Among those, the reliability of AI systems needs to be demonstrated so that the AI systems can be used with confidence by the general public.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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