Results 201 to 210 of about 694,484 (263)

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

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Evaluating Reliability in Explainable Search

2021 IEEE 2nd International Conference on Human-Machine Systems (ICHMS), 2021
Explainability in AI (XAI) is being investigated in various AI driven systems like search engines to promote trust and fairness in AI. In the context of search systems one major XAI goal is to explain the notion of similarity in text to a non-expert user like an avid reader searching for books in a digital library. What is the similarity between book A
Aditya Dey, Chandan Radhakrishna, Nishitha Nancy Lima, Suraj Shashidhar, Sayantan Polley, Marcus Thiel, Andreas Nürnberger   +6 more
openaire   +1 more source

Characterization and evaluation of standby in reliability

Proceedings of the First Workshop on DYnamic Aspects in DEpendability Models for Fault-Tolerant Systems, 2010
Standby is a topic concept in reliability. Even though several works in literature deal with standby, some aspects of standby, standby systems an standby redundancy are not or partially covered and can be further analyzed from a different perspective.
openaire   +2 more sources

Evaluating Reliability

Evaluation & the Health Professions, 1986
This study derives the economic costs of misclassification in nursing home patient classification systems. These costs are then used as weights to estimate the reliability of afunctional assessment instrument applied to 290 Veterans Administration nursing home patients.
openaire   +2 more sources

Reliability Evaluation of a Network with Delay

IEEE Transactions on Reliability, 1979
In a computer or communication network, the reliability and transfer-delay of communication are important measures of performance. This paper describes a method of evaluating the reliability of a network with delay. When network elements fail, delay is defined as the length of the shortest remaining path between two specified nodes.
Park, Yong Jin, Tanaka, Sueo
openaire   +1 more source

Reliability Evaluation by Network Decomposition

IEEE Transactions on Reliability, 1982
The method evaluates the reliability of large computer communication systems by systematic decomposition of the probabilistic graph of the system into two parts using an appropriate cutset. A technique is evolved for determining the conditional success events using both the node removal and connection multiplication methods for path enumeration.
Aggarwal, K. K., Chopra, Y. C., Bajwa, J. S.   +2 more
openaire   +1 more source