Results 151 to 160 of about 858,452 (317)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
BMC PsychologyBackground The Suicidal Intrusions Attributes Scale (SINAS) is a brief self-report measure designed to assess the frequency, distress, and controllability of suicidal intrusions—vivid, uncontrollable mental images and thoughts related to suicide or its ...
Samira Masoumian +5 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Some Comments on Egghe’s Derivation of the Impact Factor Distribution
In a recent paper, Egghe [Egghe, L. (in press). Mathematical derivation of the impact factor distribution. Journal of Informetrics] provides a mathematical analysis of the rank-order distribution of journal impact factors.
Waltman, L.R., Eck, N.J.P. van
core +1 more source
Risk-based Reliability Assessment of Subsea Control module for Offshore Oil and Gas production [PDF]
, 2014 Offshore oil and gas exploitation is principally conducted using dry or wet tree systems, otherwise called the subsea Xmas tree system. Due to the shift to deeper waters, subsea production system (SPS) has come to be a preferred technology with ...
Umofia, Anietie Nnana
core
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Two Cases in High Reliability Organizing: A Hermeneutic Reconceptualization.
In view of the primacy of organizational reliability, an exploration of what contextual and structural organization dimensions contribute to high reliability is a pertinent research issue. This dissertation attempts to answer this question in case of the
Eede, G.G.P. van den
core +1 more source
SOFTWARE RELIABILITY SIMULATION: PROCESS, APPROACHES AND METHODOLOGY
, 2011 Reliability is probably the most crucial factor to put ones hand up for in any engineering process. Quantitatively, reliability gives a measure (quantity) of quality, and the quantity can be properly engineered using appropriate reliability engineering ...
Dr.Javaid Iqbal, S.M.K. Quadri
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source