Results 101 to 110 of about 2,268,235 (274)
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
On the Reliability Function of Distributed Hypothesis Testing Under Optimal Detection
, 2019 The distributed hypothesis testing problem with full side-information is studied. The trade-off (reliability function) between the two types of error exponents under limited rate is studied in the following way.
Kochman, Yuval, Weinberger, Nir
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A Software Reliability Model Using Quantile Function
Journal of Probability and Statistics, 2014 We study a class of software reliability models using quantile function. Various distributional properties of the class of distributions are studied. We also discuss the reliability characteristics of the class of distributions.
Bijamma Thomas +2 more
doaj +1 more source
TEST RELIABILITY AS A FUNCTION OF THE NUMBER OF CHOICES PER ITEM [PDF]
, 1950 Ann F. Coward, Frederic M. Lord
openalex +1 more source
Molecular Oncology, EarlyView.This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo +6 more
wiley +1 more source
Reliability and Residual Life of Cold Standby Systems
MathematicsIn this study, we conduct a reliability characterisation study of cold standby systems. Utilising synthetic rectangular formulas and cold preparedness equivalent models for cold standby systems, we analyse the lifetimes of several typical configurations,
Longlong Liu, Xiaochuan Ai, Jun Wu
doaj +1 more source
Estimating the Reliability Function of (2+1) Cascade Model
مجلة بغداد للعلوم, 2019 This paper discusses reliability R of the (2+1) Cascade model of inverse Weibull distribution. Reliability is to be found when strength-stress distributed is inverse Weibull random variables with unknown scale parameter and known shape parameter.
Khaleel et al.
doaj +1 more source
On Nonparametric Estimation of a Reliability Function
Communications in Statistics - Theory and Methods, 2012 This article considers the properties of a nonparametric estimator developed for a reliability function which is used in many reliability problems. Properties such as asymptotic unbiasedness and consistency are proven for the estimator and using U-statistics, weak convergence of the estimator to a normal distribution is shown.
Panlop Zeephongsekul +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source