Results 71 to 80 of about 2,223,949 (308)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Culturally Appropriate Assessment of Functional Impairment in Diverse Children: Validation of the ADHD-FX Scale With an At-Risk Community Sample [PDF]

, 2017
Objective: In an effort to reduce disparities in ADHD diagnoses and treatment across cultures, the current study sought to establish initial psychometric and cultural properties of the ADHD-FX: a culturally sensitive assessment measure of functional ...
Gerdes, Alyson C., Haack, Lauren Marie
core   +1 more source

Exact two-terminal reliability of some directed networks

, 2007
The calculation of network reliability in a probabilistic context has long been an issue of practical and academic importance. Conventional approaches (determination of bounds, sums of disjoint products algorithms, Monte Carlo evaluations, studies of the
Tanguy, Christian
core   +3 more sources

EQ-5D in skin conditions: an assessment of validity and responsiveness [PDF]

, 2014
Aims and objectives This systematic literature review aims to assess the reliability, validity and responsiveness of three widely used generic preference-based measures of health-related quality of life (HRQL), i.e., EQ-5D, Health Utility Index 3 (HUI3 ...
AFN Klassen, BF O’donnell, C Moberg, D Feeny, D Papaioannou, D Revicki, DF Cella, E Christophers, E Daudén, GH Guyatt, GR Barton, J Brazier, J Brazier, J Brazier, J Dowie, J Tosh, JE Brazier, John Brazier, K Reich, L Longworth, L Longworth, L Matusiak, Louise Longworth, M Herdman, NICE, NICE, NJ Bansback, P Dolan, P Swinburn, PCM Kerkhof Van De, R Brooks, R Shikiar, R Shikiar, RJ Lasek, S Weiss, SCR Weiss, SJ Walters, T Luger, V Brodszky, Yaling Yang   +39 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Test-retest reliability of FreeSurfer measures of neurodegeneration

NeuroImage
Reliable structural brain measurements are essential for studying neurodegeneration and for designing adequately powered aging and Alzheimer’s disease (AD) research.
Henry Rusinek, Louisa Bokacheva, Haiyun Chen, Arjun Masurkar, Ricardo Osorio, Rebecca Betensky, Alok Vedvyas, Joshua Chodosh, Yongzhao Shao, Timothy Shepherd, Karyn Marsh, Thomas Wisniewski   +11 more
doaj   +1 more source

The Reliability of Subjective Well-Being Measures [PDF]

Economists are increasingly analyzing data on subjective well-being. Since 2000, 157 papers and numerous books have been published in the economics literature using data on life satisfaction or subjective well-being, according to a search of Econ Lit.1 ...
Alan B. Krueger, David A. Schkade
core  

Reliability and validity of two widely-used worry questionnaires: self-report and self-peer convergence [PDF]

, 1998
The reliability and validity of the Penn State Worry Questionnaire (PSWQ) and the Worry Domains Questionnaire (WDQ) were examined with self-ratings from a non-clinical sample of 148 students in a test-retest design across four weeks.
Borkenau, Borkovec, Cronbach, Crowne, Davey, Davey, Joachim Stöber, Joormann, Lück, McCann, McCrae, McCrae, Meyer, Molina, O'Neill, O'Neill, Shrout, Stöber, Tallis, Tallis, Watson, Wells   +21 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

An assessment of validity and responsiveness of generic measures of health-related quality of life in hearing impairment [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the ...
A Vuorialho, A Vuorialho, AK Cheng, AS Pickard, BG Bichey, CA Marra, CS Palmer, D Feeny, D Feeny, D Papaioannou, DL Streiner, DS Dalton, G Hawthorne, G Kobelt, GR Barton, GR Barton, GW Torrance, GWJA Damen, HY Lee, J Brazier, J Brazier, J Brazier, JE Brazier, JE Brazier, John Brazier, JPC Grutters, L Longworth, L Smith-Olinde, Louise Longworth, M Joore, MA Joore, MA Joore, MAB Joore, MKS Hol, P Dolan, PFM Krabbe, PK Sand, R Brooks, R Harper, RES Lovett, TH Sach, Y Yang, Yaling Yang   +42 more
core   +3 more sources