Results 101 to 110 of about 775,094 (277)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Civil aircraft advanced avionics architectures - an insight into saras avionics, present and future perspective [PDF]
, 2009 Traditionally, the avionics architectures being implemented are of federated nature, which means that each avionics function has its own independent, dedicated fault-tolerant computing resources.
Ananda, CM
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Speed Estimation of Multiple Moving Objects from a Moving UAV Platform
ISPRS International Journal of Geo-Information, 2019 Speed detection of a moving object using an optical camera has always been an important subject to study in computer vision. This is one of the key components to address in many application areas, such as transportation systems, military and naval ...
Debojit Biswas +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Deep Learning-Based Visual Analytics for Efficiency and Safety Optimization in Power Infrastructure
EngThe paper presents a comprehensive deep learning-based framework for automated visual inspection of overhead power line infrastructure using unmanned aerial vehicles. Traditional manual and helicopter inspections are costly, time-consuming, and hazardous
Olga Vladimirovna Afanaseva +2 more
doaj +1 more source
THE DISCRETIZATION OF THE POLARIZED SIGNAL
Научный вестник МГТУ ГА, 2018 Often, the monitoring systems solution of remote sensing problems, recognition (classification, discrimination) of radar objects using radio polarimetry methods is required in real time mode with the display of the current information on the radar ...
P. E. Korneev
doaj +1 more source
Human-machine diversity in the use of computerised advisory systems: a case study [PDF]
, 2003 Computer-based advisory systems form with their users composite, human-machine systems. Redundancy and diversity between the human and the machine are often important for the dependability of such systems.
Alberdi, E. +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source