Results 101 to 110 of about 1,877,205 (300)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Verification of the AIS service availability model based on dynamic data streams recorded from three receiving stations in the Polish coastal area

open access: yesArchives of Transport
The reliability aspects of the operation of radio navigation systems constitute a crucial element for the safety of maritime navigation.. Technological progress in ship traffic monitoring is achieved through the design of ship systems and shore ...
Krzysztof Jaskolski   +1 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A Health Monitoring Method for Li-ion Batteries Based on Profust Reliability Theory

open access: yesChemical Engineering Transactions, 2013
This paper presents an applicable health monitoring method for Li-ion batteries based on profust reliability theory. The word “profust” derives from “probability” and “fuzzy-state”, which means that the profust reliability theory is a kind of fuzzy ...
Z.Y. Zhao, Q. Quan, K.Y. Cai
doaj   +1 more source

The Improvement Program in Nonrelativistic Lattice QCD

open access: yes, 1993
Progress in the improvement program in nonrelativistic lattice QCD is outlined. The leading radiative corrections to the heavy-quark mass renormalization, energy shift, and two important kinetic coupling coefficients are presented.
Colin J. Morningstar   +5 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Laplace transform technique and probabilistic analysis-based hypothesis testing in medical and engineering applications

open access: yesOpen Physics
This study introduces a novel nonparametric hypothesis test designed to evaluate exponentiality against the New Better than Renewal Used in Moment Generating Function (NBRUmgf) class.
Bakr Mahmoud E.   +3 more
doaj   +1 more source

BIONIC ROBOT FISH GRADIENT RELIABILITY OPTIMIZATION DESIGN BASED ON IMPROVED QUANTUM EVOLUTIONARY ALGORITHM

open access: yesJixie qiangdu, 2022
In order to improve the working reliability of the biomimetic robotic fish, put forward a gradient reliability robust optimization design method method which is applied to the biomimetic robotic fish.Taken the bionic killer whale as the research object ...
LI MingHao   +3 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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