Results 111 to 120 of about 1,877,205 (300)

Automatization techniques for processing biomedical signals using machine learning methods [PDF]

open access: yes, 2008
The Signal Processing Group (Department of Signal Theory and Communications, University Carlos III, Madrid, Spain) offers the expertise of its members in the automatic processing of biomedical signals.
Artés Rodríguez, Antonio
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Statistical Science and Philosophy of Science: Whrer Do / Should They Meet in 2011 (and Beyond)? [PDF]

open access: yes
philosophy of science, philosophy of statistics, decision theory, likelihood, subjective probability, Bayesianism, Bayes theorem, Fisher, Neyman and Pearson, Jeffreys, induction, frequentism, reliability ...
Deborah Mayo
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Using a Log-normal Failure Rate Distribution for Worst Case Bound Reliability Prediction [PDF]

open access: yes, 2003
Prior research has suggested that the failure rates of faults follow a log normal distribution. We propose a specific model where distributions close to a log normal arise naturally from the program structure.
Bishop, P. G., Bloomfield, R. E.
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

NUMERICAL SIMULATION AND RELIABILITY SENSITIVITY ANALYSIS OF BIONIC KILLER WHALES’S LOAD CHARACTERISTIC

open access: yesJixie qiangdu, 2021
As a kind of bionic robot fish,bionic killer whale played an important role in ocean development and scientific investigation. Based on the flapping wing movement theory,the bionic killer whale’s mechanism was analyzed,its instantaneous load was ...
LI MingHao   +5 more
doaj  

Software reliability experiments data analysis and investigation [PDF]

open access: yes
The objectives are to investigate the fundamental reasons which cause independently developed software programs to fail dependently, and to examine fault tolerant software structures which maximize reliability gain in the presence of such dependent ...
Caglayan, Alper K., Walker, J. Leslie
core   +1 more source

Factor Structure and Psychometric Properties of Cognitive-Behavioral Scales in Caregivers of Persons with Dementia [PDF]

open access: yes, 2018
Background/Purpose Caregiving can be costly to dementia caregivers\u27 well-being. Assessing the factor structure and psychometric properties of Cognitive-Behavioral Scales in dementia caregivers is an essential step in addressing the gap in the current ...
Bekhet, Abir K.   +1 more
core   +1 more source

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