Results 91 to 100 of about 3,281,314 (230)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Journal of Research in Medical Sciences, 2014 Background: Oropharyngeal dysphagia following stroke enhances the risk of dehydration, malnutrition, aspiration pneumonia, persistent disablement, and even death. Screening of dysphagia has been shown to positively change health outcomes.
Marziyeh Poorjavad, Shohreh Jalaie
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Computing the probability mass function of the maximum flow through a reliable network [PDF]
In this paper we propose a fast state-space enumeration based algorithm called TOP-DOWN capable of computing the probability mass function of the maximum s-t flow through reliable networks.
Sharma, Megha, Ghosh, Diptesh
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On Cloud-based multisource Reliable Multicast Transport in Broadband Multimedia Satellite Networks [PDF]
, 2012 Multimedia synchronization, Software Over the Air, Personal Information Management on Cloud networks require new reliable protocols, which reduce the traffic load in the core and edge network.
ABDO, EMNET TSADIKU
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Reliable and Faithful Generative Explainers for Graph Neural Networks
Machine Learning and Knowledge ExtractionGraph neural networks (GNNs) have been effectively implemented in a variety of real-world applications, although their underlying work mechanisms remain a mystery.
Yiqiao Li +4 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Reliable algorithms for computing minimal dynamic covers for descriptor systems [PDF]
, 2004 Minimal dimension dynamic covers play an important role in solving the structural synthesis problems of minimum order functional observers or fault detectors, or in computing minimal order inverses or minimal degree solutions of rational equations.
A. Varga, Varga, Andras
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