Results 31 to 40 of about 805,471 (343)

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Matching missions: hunger relief programs and impact of food donation partners in Northwest Arkansas [PDF]

open access: yes, 2015
In 2012 and 2013, Arkansas ranked first in the nation in food insecurity in both categories of “low food secure” (21.2%) and “very low food secure” (8.4%).
Popp, Jennie, West, Amy May
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Media Review: A Church Leader's Tool Kit to the Syrian Refugee Crisis

open access: yesInterdisciplinary Journal of Partnership Studies, 2016
Judy O'Fallon reviews the online resource A Church Leader’s Tool Kit to the Syrian Refugee Crisis, published by the non-profit organization World Relief.
Judy O'Fallon
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

International organizations and the problem of child health, 1945-1960 [PDF]

open access: yes, 2003
Faced with planning mass relief campaigns in liberated Europe in the aftermath of the Second World War, the United Nations Relief and Rehabilitation Administra­tion relied heavily on cheap supplies of skimmed milk from surplus production in northern ...
Gillespie, James A.
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The international humanitarian response to famine in Tigray, Ethiopia:lessons from the Nigerian Civil War, 1967-1970

open access: yesGlobal Health Action, 2022
The Tigray crisis in Ethiopia is a grave humanitarian catastrophe with causes and consequences that resemble the Nigerian Civil War that ended with the defeat of secessionist Biafra five decades ago.
James F. Phillips   +2 more
doaj   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

Imam Khomeini Relief Foundation, an Organization by the People for the People [PDF]

open access: yesIranian Journal of Public Health, 2009
Imam Khomeini Relief Foundation (IKRF) was officially established on March 5th 1979, to aid the underprivileged, allevi­ate poverty and improve the self sufficiency of the needy people.
MH Nicknam
doaj   +1 more source

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