Results 31 to 40 of about 819,198 (316)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Nurses Alumni Association Bulletin, Fall 1998 [PDF]
1998-1999 Meeting Date Calendar 1999 Annual Luncheon & Meeting Notice Fall Social Officers and Committee Chairs Bulletin Publication Committee The President\u27s Message Treasurer\u27s Report News About Our Graduates Highlight Of 1998 Operation Smile ...
Piersol, Betty +3 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Imam Khomeini Relief Foundation, an Organization by the People for the People [PDF]
Imam Khomeini Relief Foundation (IKRF) was officially established on March 5th 1979, to aid the underprivileged, alleviate poverty and improve the self sufficiency of the needy people.
MH Nicknam
doaj +1 more source
A model of collaborative management in disaster relief
This paper elaborates on the collaborative management model for disaster relief by using systematic reviews. The focus point in humanitarian aids actors who collaborate in disaster relief approach.
Phuengpha Noppawan +3 more
doaj +1 more source
The Tigray crisis in Ethiopia is a grave humanitarian catastrophe with causes and consequences that resemble the Nigerian Civil War that ended with the defeat of secessionist Biafra five decades ago.
James F. Phillips +2 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Living, Aging, and Dying in Healthy and Just Societies: Life Lessons From my Father [PDF]
My father passed away at 102 years old. He lived, aged, and died well. But that is rare in the United States and globally. The World Health Organization defines palliative care “throughout the life course” as improving quality of life for patients and ...
Gostin, Lawrence O.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

