Results 71 to 80 of about 4,641,257 (344)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A three-view geometric perspective on mountainous small watersheds: Parameter development and spatial pattern analysis

Ecological Indicators
Mountainous small watersheds are fundamental geomorphic units that integrate hillslope, channel, and valley-floor processes and exert first-order controls on runoff routing, sediment transfer, and landscape organization in complex terrain.
Zhengyang Li, Ting Deng, Pei Xu, Jianjian He, Yafeng Lu, Qin Liu   +5 more
doaj   +1 more source

An assessment approach for non-governmental organizations in humanitarian relief logistics and an application in Turkey

Technological and Economic Development of Economy, 2018
The ever-increasing natural disasters have been causing the loss of lives, properties and resources. By the preparedness and response ability of non-governmental organizations, it is aimed to minimize these losses.
Erkan Celik, Alev Taskin Gumus
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Leadership of Humanitarian Organizations Working in Less Developed Countries: A Best Practices Analysis [PDF]

, 2016
Many people from the developed world, who intend to help the poor in less developed countries, actually end up doing harm by creating more dependence, demonstrating ignorance of the local culture, not understanding the importance of long-term ...
Oliphant, John
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Self-Organizing of Waves and Sandy Bottom Relief—Laboratory Experiments

Journal of Marine Science and Engineering
Many studies suggest that, as waves propagate toward the shore, mutual adaptation (self-organization) occurs between the wave transformation and the bottom relief. However, the details of this process are unknown.
Yana Saprykina, Sergey Kuznetsov
doaj   +1 more source

Haiti Earthquake January 2010: What Actions and Policies Can the Government of Haiti Implement to Improve Emergency Management Response [PDF]

, 2011
In 2010, Haiti experienced a devastating earthquake that destroyed much of its capital city and the governmental offices that should have guided the response to the disaster.
Cohen, Steve
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source