Results 41 to 50 of about 166,490 (310)
TYPES OF RELIEF ELEMENTS ON BANKNOTES AND WAYS TO IMITATE THEM
The article is devoted to the consideration of methods for imitation of relief elements and perforation in the manufacture of counterfeit banknotes. In the manufacture of banknotes in modern conditions, the latest scientific and technical achievements are used.
Nataliia Zubova +3 more
openaire +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Background and AimsSince alcohol use disorders are among the most prevalent and destructive mental disorders, it is critical to address factors contributing to their development and maintenance.
Verena Ertl +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Surface-relief type Bragg grating reflector fabricated after overcladding removal
A novel silica-based Bragg grating reflector on Si substrate is described. The reflector is formed on a core whose overcladding layer is removed by RIE until it is level with the core surface. The reflector which comprises a rectangular relief type grating only 1.6 mm long has the advantages of a highly controllable Bragg wavelength and a high ...
M. Ishii +3 more
openaire +1 more source
Surge-type Uisu glacier and its undisturbed forefield relief, Eastern Pamir, Tajikistan
Abstract The surge-type Uisu glacier and its forefield in the Tajik part of Eastern Pamir are described. To this end, 1977–2019 Landsat satellite imagery, the DEM, and a high-resolution orthophotomap were used, and detailed geomorphological mapping was carried out.
Bogdan Gądek +2 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Coastal Dunes of the Baltic Sea Shores: A Review
The article summarises results of studies conducted along the Baltic Sea sandy coasts by scientists involved in coastal dune research, and presents an attempt to describe the types and distribution of dune coasts.
Łabuz Tomasz Arkadiusz +7 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

