Results 41 to 50 of about 2,881,633 (243)

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

open access: yesAdvanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho   +6 more
wiley   +1 more source

Sofia Singler, The Religious Architecture of Alvar, Aino and Elissa Aalto

open access: yes
A review of Sofia Singler's book The Religious Architecture of Alvar, Aino and Elissa ...
Watson, V.A.
core   +3 more sources

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

open access: yesAdvanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng   +15 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

Die frühe Gotik im Heiligen Römischen Reich: Neue Fragen, Methoden, Ergebnisse und Lücken in der Forschung

open access: yesPerspective, 2014
Die jüngere Forschung zur frühen gotischen Architektur in Deutschland wird vor allem durch die Ergebnisse von Restaurierungsmaßnahmen sowie methodisch komplexe Bauuntersuchungen bestimmt. Dies trifft besonders für die Bauten in der ehemaligen DDR zu, die
Bruno Klein
doaj   +1 more source

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

open access: yesAdvanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali   +2 more
wiley   +1 more source

MXene‐Derived Highly Oriented TiN Enables Ta3N5 Photoanodes for Transmission‐Mode Bias‐Free Solar Water Splitting

open access: yesAdvanced Energy Materials, EarlyView.
This work reports 2D MXene‐derived TiN thin films with (111)‐preferred orientation for transparent Ta3N5 photoanodes, demonstrating effective electron transfer behavior. All‐nitride electron‐collection architecture based on MXene‐derived TiN and n‐GaN resolves a long‐standing materials bottleneck between photocarrier transport and light transmission in
Jin Wook Yang   +10 more
wiley   +1 more source

Transformation et adaptation des formes architecturales européennes en Nouvelle-France aux xviie et xviiie siècles

open access: yesPerspective, 2008
The first studies conducted on the architecture of French Canada attempted to interpret it as a throwback to the Middle Ages, one that, once exported to the Americas, rapidly developed into a unique and independent architectural tradition.
Marc Grignon
doaj   +1 more source

Personality and religious maturity [PDF]

open access: yes, 2009
A sample of 226 students attending seminaries, theological colleges, and bible schools completed Newton Malony’s Religious Status Inventory (as a measure of religious maturity) alongside the short-form Revised Eysenck Personality Questionnaire.
Francis, Leslie J., Pocock, Nigel
core   +1 more source

MolMiner: Toward Controllable, Three‐Dimensional‐Aware, Fragment‐Based Molecular Design

open access: yesAdvanced Intelligent Discovery, EarlyView.
MolMiner is a fragment‐based, geometry‐aware, and order‐agnostic generative model for molecular design with strong inductive biases. Using symmetry‐aware fragment assembly, dynamic three‐dimensional geometry, and multi‐property conditioning, MolMiner enables interpretable and controllable molecular generation.
Raul Ortega‐Ochoa   +2 more
wiley   +1 more source

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