Results 31 to 40 of about 26,322 (262)

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Stosunki majątkowe między parafią zakonną a domem zakonnym

open access: yesAnalecta Cracoviensia, 2013
This article presents the problematic concerning the property relations between the religious parish and the religious house. According to the Author these relations are founded on two basic principles: the autonomy of the two juridical persons, i.e ...
Piotr Skonieczny
doaj   +1 more source

Religious Establishment and Autonomy

open access: yesConstitutional Commentary, 2008
Kent Greenawalt claims that one rationale for nonestablishment of religion is personal autonomy. If, however, the law is barred from manipulating people in religious directions (and thus violating their autonomy), while it remains free to manipulate them in nonreligious directions (and thus violate their autonomy in exactly the same way), autonomy as ...
openaire   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

Separatismo (Separatism)

open access: yesMoneta e Credito, 2012
Most of the world's trouble spots arise from separatism, passionate demand for autonomy or independence by ethnic minorities--Kosovo, ETA, Kashmir, Tamil Tigers, East Timor and many others. This article tries to explain this phenomenon.
H. W. Arndt
doaj   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola   +10 more
wiley   +1 more source

Neutralité de l’État et dissensions ecclésiales : réflexions à partir d’un arrêt récent de la Cour européenne

open access: yesRevue du Droit des Religions, 2020
The European Court of Human Rights recognizes a right of religious organizations to autonomy, both doctrinal and disciplinary. It set this principle aside in the case of Tothpal and Szabo v.
Nicolas Bauer
doaj   +1 more source

A Large Scale Multi‐Modal Workflow for Battery Characterization: From Concept to Implementation

open access: yesAdvanced Energy Materials, EarlyView.
Isolated characterization techniques produce independent datasets and single‐property insights. However, progressively more holistic interpretations of battery‐material behavior is needed in the future. Here we demonstrate a coordinated multimodal workflow enabling the correlation of heterogeneous datasets and the construction of multidimensional ...
François Cadiou   +34 more
wiley   +1 more source

Governing Diversity: Reflections on the Doctrine and Tradition of Religious Accommodation in Islam

open access: yesJournal of Islamic Thought and Civilization, 2020
The problématique of governing diversity has attracted a great deal of scholarly attention but literature has largely overlooked the challenges appertaining to growing religious diversity in many places.
Dr. Muhammad Mushtaq   +1 more
doaj   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

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