Results 61 to 70 of about 102,529 (267)
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Bir Değişim Risâlesi: “Teṣādüfü’ş-Şerʿi ve’z-Zemān…”
Bu araştırma notu 20.yüzyılın başlarında Kazan bölgesinde aktif olan Tatar alimi Şākircān Ḥamīdī veonun Teṣādüfü’ş-Şerʿi ve’z-Zemān fī Beldetin Maʿrūfetin bi-Ḳazān (Şeriatve Zamanın Kazan Diye Maruf Bir Beldede Karşılaşması) başlıklı kısa ...
İsmail Hakkı Ünal
doaj
ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng +9 more
wiley +1 more source
Receptogenesis in a Vascularized Robotic Embodiment
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov +8 more
wiley +1 more source
A Large Scale Multi‐Modal Workflow for Battery Characterization: From Concept to Implementation
Isolated characterization techniques produce independent datasets and single‐property insights. However, progressively more holistic interpretations of battery‐material behavior is needed in the future. Here we demonstrate a coordinated multimodal workflow enabling the correlation of heterogeneous datasets and the construction of multidimensional ...
François Cadiou +34 more
wiley +1 more source
Religious and Cultural Change in Three Generations
This study is a field research that aims to investigate the formation of the differences in attitudes assumed by generations towards religious and cultural values in today’s changing socio-cultural environment.
Mustafa Bakırcı
doaj
This work reports 2D MXene‐derived TiN thin films with (111)‐preferred orientation for transparent Ta3N5 photoanodes, demonstrating effective electron transfer behavior. All‐nitride electron‐collection architecture based on MXene‐derived TiN and n‐GaN resolves a long‐standing materials bottleneck between photocarrier transport and light transmission in
Jin Wook Yang +10 more
wiley +1 more source
Church services and religious change in Burundi
In Burundi, weekly services are the primary point of contact between churches and their followers, with most of the population attending. These gatherings provide churches with a strategic platform to attract and retain members.
Pedro Naso, Jean Budurha
doaj +1 more source
The establishment of educational institutes which mainly focus on English language course at Kampung Inggris (the Village of English) of Pare-Kediri plays pivotal role in the process of transformation of the local society especially in socio-religious ...
Ahmad Subakir
doaj +1 more source
Measuring Nutrition Security Using the Consumer Food Data System Datasets
ABSTRACT Nutrition security is an emerging concept lacking a consensus definition, conceptualization, or standardized measure. This perspectives manuscript synthesizes findings from two previously published analyses to assess the feasibility of using available measures of key dimensions of nutrition security from two Consumer Food Data System (CFDS ...
Vibha Bhargava +2 more
wiley +1 more source

