Results 31 to 40 of about 4,696,159 (302)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Women and Water

Matrix
The relationships between women and water are deep and fluid, informing the definition of the feminine, the roles assigned to women, and the very perception of life.
Linnéa Rowlatt, Marie-Françoise Guédon   +1 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Philosophical pragmatism and religious belief: interpreting Christian non-realism through john Dewey and Richard Rorty [PDF]

, 1996
In this thesis I consider the account of religious non-realism in the work of Don Cupitt and in other prominent writers belonging to the 'Sea of Faith' network. I argue that the appropriate context of the non-realists understanding of religious belief is
Knight, P.J., Knight, Philip J.
core  

Three religious orientations and five personality factors : an exploratory study among adults in England [PDF]

, 2010
In order to explore the power of the five factor model of personality to explain individual differences recorded on measures of the three religious orientations, a sample of 198 adults in England completed established measures of the three religious ...
Rachel Clarke, McIlroy, David, Robbins, Mandy, Pritchard, Lowri, Lowri Pritchard, Mandy Robbins, David McIlroy, Francis, Leslie J., Clarke, Rachel, Francis, Leslie, Leslie Francis   +10 more
core   +1 more source

Correlation between secular state and religious orientation: Internal and external motives of madrasa students [PDF]

Pharos Journal of Theology
The purpose of the study was to analyse the mechanisms of regulation of Islamic education in different countries and their influence on the religious orientation of students at Islamic schools (madrasas).
Rakhymzhan Rashimbetov, Nauryzbay Utpinov, Gilimbek Mazhiyev, Nurlan Kairbekov   +3 more
doaj   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Futures Studies on the Governance of Religious Propagation in Iran: Analysis of Trends, Drivers, and Strategies [PDF]

Religion & Communication
This study investigates the potential futures of religious advertising governance in Iran, offering strategies to enhance its effectiveness amidst accelerating technological, social, and cultural transformations.
jalal rizaneh
doaj   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source