Results 31 to 40 of about 79,147 (261)
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Advanced Science, EarlyView.Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Advanced Science, EarlyView.In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian +13 more
wiley +1 more source
A Mosaic of Secularization through the Lens of Education:
Філософія освітиThis review examines the interdisciplinary volume “Educational Secularization within Europe and Beyond: The Political Projects of Modernizing Religion through Education Reform” (edited by Mette Buchardt, 2025), which explores processes of educational ...
Вікторія Кришмарел
doaj +1 more source
Advanced Science, EarlyView.A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang +6 more
wiley +1 more source
Oriental Studies, 2020 Introduction. Religious policies of the Russian Empire in early modern history is a topical issue of historiography. An important (though poorly researched) aspect of this question is the role of Kalmyk Christian elites.
Andrey S. Ryazhev
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Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci +4 more
wiley +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Cultural capital influences a wide range of social and economic outcomes, yet quantitative measures suitable for policy analysis remain limited. We develop county‐level cultural capital indices for the US based on Bourdieu's framework of objectified, embodied, and institutionalized cultural capital.
Pratyoosh Kashyap +2 more
wiley +1 more source
Classica Cracoviensia, 2020 This article deals with Julian the Apostate’s religious policy and its relationship with the renewal of both the Roman state and the morals of Roman society during the emperor’s reign.
Anna Mleczek
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Vietnam’s Religious Policy: Navigating the Path to Religious Freedom
Qeios, 2023 Vietnam is located in Southeast Asia and the country has a large population. Vietnam’s population would reach to 100 million people ranked 15th in the world[1]. Vietnam has undergone significant changes throughout its history, reflecting the country's complex socio-political landscape.
openaire +1 more source
Impact of Digital Ability and Rice Technology Adoption on Rice Farming Performance in Benin
Agribusiness, EarlyView.ABSTRACT This study examines the combined effects of digital ability and the adoption of various rice technologies among smallholder rice farmers, using GPS‐spatially matched data sources that include household surveys and a general census of rice value chain actors in Benin.
Landry Bellarmin Kassa, Takeshi Sakurai
wiley +1 more source