Results 71 to 80 of about 161,099 (297)

Salafi Ideology and the Question of Women Empowerment among Kenyan Muslims

open access: yesJurnal Kawistara
Muslim groups that promote strict religious norms like Salafis are often associated with male dominant culture. Such a patriarchal maybe put on a question in the context in the recent global trend that significantly altered the circumstances for Muslim ...
Fatuma Kassim Mwatamu   +2 more
doaj   +1 more source

STAT6 Activation Exacerbates Ferroptosis in Airway Epithelium by Inhibiting PRKN‐Mediated Mitophagy in Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang   +7 more
wiley   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu   +15 more
wiley   +1 more source

The Methodology of Imam Bukhārī in Al Tārīkh Al Kabīr for Criticism, Praise and Biographies of Narrators

open access: yesJournal of Islamic and Religious Studies, 2019
Muḥadithīn have played a dynamic role in the preservation and compilation of Ḥadīth of the Prophet (SAW). Among them the contribution of Imam Bukhārī is unavoidable and remarkable in the field of Ḥadīth and its sciences.
Muhammad Noman   +2 more
doaj   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

open access: yesAdvanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria   +5 more
wiley   +1 more source

Etikk i praksis gjennom 10 år (2007-2017): 10 years of Nordic applied ethics

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2017
The editors of Etikk i praksis are pleased to introduce six papers in this open-themed issue for the journal’s 10th year anniversary.
Allen Alvarez   +2 more
doaj   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

open access: yesAdvanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang   +21 more
wiley   +1 more source

The normative dimensions of new technologies

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2015
This special issue of Etikk i praksis features papers that articulate and discuss approaches and methodology that seek to make normative research activity and research output productive in contexts of ongoing societal and technological decision-making ...
Lars Ursin   +2 more
doaj   +1 more source

Critical Electrochemistry Technologies Applicable in Space Exploration

open access: yesAdvanced Science, EarlyView.
The available resources in space and discuss the application scenarios and challenges of electrochemical methods in four critical domains is analyzed: metallurgical processing of mineral resources, water resources utilization, carbon cycle management in extraterrestrial habitats, and electrical energy storage.
Ruisi Xu   +4 more
wiley   +1 more source

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