Results 31 to 40 of about 59,622 (239)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Local Aspects of Avian Non-REM and REM Sleep [PDF]

Frontiers in Neuroscience, 2019
Birds exhibit two types of sleep that are in many respects similar to mammalian rapid eye movement (REM) and non-REM (NREM) sleep. As in mammals, several aspects of avian sleep can occur in a local manner within the brain. Electrophysiological evidence of NREM sleep occurring more deeply in one hemisphere, or only in one hemisphere-the latter being a ...
Rattenborg, Niels C., van der Meij, Jacqueline, Beckers, Gabriël J. L., Lesku, John A.   +3 more
openaire   +6 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Radioactivity and geochemical characteristics of cryoconite on the Tien Shan glacier

Scientific Reports
The article reports on a study of the cryoconite contamination with anthropogenic and natural radionuclides, as well as ore caused elements, conducted on the Tuyuksu Glacier.
Alexey Miroshnikov, Adilzhan Serikov, Alexander Kokarev, Mariya Severinenko, Svetlana Lennik, Pavel Kharkin, Diana Akhmetzhanova, Marina Krasnopyorova, Olga Milts, Varvara Makarova, Viktor Morenko, Vadim Fedulov, Vassiliy Kapitsa, Nikolay Kasatkin, Enver Asadulin, Galina Nadyarnykh, Sayabek Sakhiev   +16 more
doaj   +1 more source

Why Does REM Sleep Occur? A Wake-up Hypothesis

Frontiers in Systems Neuroscience, 2011
Brain activity differs in the various sleep stages and in conscious wakefulness. Awakening from sleep requires restoration of the complex nerve impulse patterns in neuronal network assemblies necessary to re-create and sustain conscious wakefulness ...
Dr. W. R. eKlemm
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Correlations Between Adolescent Processing Speed and Specific Spindle Frequencies

Frontiers in Human Neuroscience, 2015
Sleep spindles are waxing and waning thalamocortical oscillations with accepted frequencies of between 11 and 16 Hz and a minimum duration of 0.5 seconds.
Rebecca S. Nader, Rebecca S. Nader, Carlyle T. Smith   +2 more
doaj   +1 more source

Hibernation in a primate: does sleep occur? [PDF]

Royal Society Open Science, 2016
During hibernation, critical physiological processes are downregulated and thermogenically induced arousals are presumably needed periodically to fulfil those physiological demands.
Marina B. Blanco, Kathrin H. Dausmann, Sheena L. Faherty, Peter Klopfer, Andrew D. Krystal, Robert Schopler, Anne D. Yoder   +6 more
doaj   +1 more source

Non-REM and REM/paradoxical sleep dynamics across phylogeny

Current Opinion in Neurobiology, 2021
All animals carefully studied sleep, suggesting that sleep as a behavioral state exists in all animal life. Such evolutionary maintenance of an otherwise vulnerable period of environmental detachment suggests that sleep must be integral in fundamental biological needs.
James B, Jaggard, Gordon X, Wang, Philippe, Mourrain   +2 more
openaire   +2 more sources

Characterization of a Recyclate‐Based MgO‐Steel Composite As‐Sintered Inert Anode Candidate After Exposure to Cryolite Electrolysis

Advanced Engineering Materials, EarlyView.
Carbon‐free inert anodes are essential for decarbonizing aluminum electrolysis. This study investigates a recyclate‐based MgO‐316L steel composite anode tested under galvanostatic Hall–Héroult conditions in cryolite at 1000°C. Microstructural analysis reveals selective MgO fluorination, spinel and oxide layer formation, electrolyte infiltration, and ...
Serhii Yaroshevskyi, Alexander Adamczyk, Nora Brachhold, Gert Schmidt, Jana Hubálková, R. Gumeniuk, Alexandros Charitos, Christos G. Aneziris   +7 more
wiley   +1 more source