Results 131 to 140 of about 696,853 (368)

Neuronal avalanches differ from wakefulness to deep sleep - evidence from intracranial depth recordings in humans [PDF]

, 2013
Neuronal activity differs between wakefulness and sleep states. In contrast, an attractor state, called self-organized critical (SOC), was proposed to govern brain dynamics because it allows for optimal information coding.
Le Van Quyen, Michel, Priesemann, Viola, Valderrama, Mario, Wibral, Michael   +3 more
core   +3 more sources

Progranulin Mutation Manifesting as Parkinson Disease: A Case Series from the PADUA‐CESNE Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Mutations in progranulin (GRN) are associated with frontotemporal dementia, although a Parkinson disease (PD) phenotype is uncommon, especially in young patients. Cases We report three subjects from the PADUA‐CESNE cohort, meeting diagnostic criteria for PD, with onset under age 55.
Giulia Bonato, Marta Campagnolo, Aron Emmi, Valentina Misenti, Tommaso Carrer, Carmelo Fogliano, Leonardo Salviati, Miryam Carecchio, Angelo Antonini   +8 more
wiley   +1 more source

Association of symptoms of insomnia and sleep parameters among kidney transplant recipients [PDF]

, 2017
Objective: Insomnia complaints are frequent among kidney transplant (kTx) recipients and are associated with fatigue, depression, lower quality of life and increased morbidity.
Bodizs, Robert, Czira, Maria E., Gombos, Ferenc, Lazar, Alpar S., Lazar, Zsolt I., Lindner, Anett V., Molnar, Miklos Z., Mucsi, Istvan, Novak, Marta, Papp, Istvan, Ronai, Katalin Z., Szentkiralyi, Andras, Zoller, Rezso   +12 more
core   +1 more source

Motor Cortex Disinhibition Correlates with Olfactory Dysfunction in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Motor cortex disinhibition, as measured by impaired short‐interval intracortical inhibition (SICI) using transcranial magnetic stimulation (TMS), is a well‐established feature of Parkinson's disease (PD). However, its substantial variability among patients remains unexplained, prompting questions about its origin, clinical relevance,
Claudia Ammann, Cristina Pagge, Emmanuelle Wilhelm, Chiara Galletti, Tamara Jimenez‐Castellanos, Michele Matarazzo, Agustina Ruiz‐Yanzi, Carmen Gasca‐Salas, Raul Martínez‐Fernández, Fernando Alonso‐Frech, Antonio Oliviero, José A. Obeso, Guglielmo Foffani   +12 more
wiley   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Relationship between rapid eye-movement activity during nocturnal sleep and developmental quotient in infants with developmental disabilities [PDF]

, 2009
－Rapid eye-movement (REM) activity during nocturnal sleep was investigated in 27 infants with developmental disabilities. A relationship was found between REM sleep degree of REM and developmental psychomotor function.
Kamikawa Yasuko, Shibagaki Masamitsu
core   +1 more source

The Neurobiological Mechanisms and Treatments of REM Sleep Disturbances in Depression

Current Neuropharmacology, 2015
Most depressed patients suffer from sleep abnormalities, which are one of the critical symptoms of depression. They are robust risk factors for the initiation and development of depression.
Yi-Qun Wang, Rui-Xi Li, Meng-Qi Zhang, Ze Zhang, W. Qu, Zhi-Li Huang   +5 more
semanticscholar   +1 more source

Distinct Longitudinal Clinical‐Neuroanatomical Trajectories in Parkinson's Disease Clinical Subtypes: Insight toward Precision Medicine

Movement Disorders, EarlyView.
ABSTRACT Background Parkinson's disease (PD) varies widely across individuals in clinical manifestations and course of progression. Identification of distinct biological subtypes could explain this heterogeneity, identify its pathophysiology, and predict disease progression. Objectives Our aim was to compare longitudinal clinical trajectories and brain
Seyed‐Mohammad Fereshtehnejad, Roqaie Moqadam, Houman Azizi, Ronald B. Postuma, Mahsa Dadar, Anthony E. Lang, Connie Marras, Yashar Zeighami   +7 more
wiley   +1 more source

The supramammillary nucleus and the claustrum activate the cortex during REM sleep

Science Advances, 2015
Plasticity and cortical activation during REM sleep is shown by a subset of cortical and hippocampal neurons. Evidence in humans suggests that limbic cortices are more active during rapid eye movement (REM or paradoxical) sleep than during waking, a ...
Leslie Renouard, Francesca Billwiller, K. Ogawa, O. Clément, N. Camargo, Mouaadh Abdelkarim, N. Gay, Céline Scoté-Blachon, Rouguy Touré, P. Libourel, P. Ravassard, D. Salvert, C. Peyron, B. Claustrat, L. Léger, Paul Antoine Salin, G. Malleret, P. Fort, P. Luppi   +18 more
semanticscholar   +1 more source

Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients

Movement Disorders, EarlyView.
Abstract Background Hereditary ataxias are genetically diverse, yet up to 75% remain undiagnosed due to technological and financial barriers. The GGC repeat expansion in ZFHX3, responsible for spinocerebellar ataxia type 4 (SCA4), has only been described in individuals of Northern Europeandescent.
Paula Saffie‐Awad, Abraham Moller, Kensuke Daida, Pilar Alvarez Jerez, Zhongbo Chen, Zachary B. Anderson, Mariam Isayan, Kimberly Paquette, Sophia B. Gibson, Madison Fulcher, Abigail Miano‐Burkhardt, Laksh Malik, Breeana Baker, Paige Jarreau, Henry Houlden, Mina Ryten, Bida Gu, Mark J.P. Chaisson, Danny E. Miller, Pedro Chaná‐Cuevas, Cornelis Blauwendraat, Andrew B. Singleton, Kimberley J. Billingsley   +22 more
wiley   +1 more source