Results 191 to 200 of about 49,936 (298)

Sex‐based disparities in dopamine agonist response in patients with restless legs syndrome

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary This study aimed to investigate sex‐related differences in the response to ropinirole and pramipexole in patients with restless legs syndrome (RLS). By analysing clinical parameters and polysomnographic (PSG) findings, we sought to elucidate the potential factors related to sex disparities modulating treatment responses and sleep quality in RLS.
Maria P. Mogavero, Elena Antelmi, Giuseppe Lanza, Sara Marelli, Alessandra Castelnuovo, Michele Tinazzi, Lourdes M. DelRosso, Rosalia Silvestri, Raffaele Ferri, Luigi Ferini Strambi   +9 more
wiley   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

Cardiovascular Activity Predominantly Modulates Brain Dynamics in Non-REM Sleep Transitions. [PDF]

Ann N Y Acad Sci
Catrambone V, Faraguna U, Valenza G.
europepmc   +1 more source

Sleep and cardiac autonomic modulation in older adults: Insights from an at‐home study with auditory deep sleep stimulation

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The autonomic nervous system regulates cardiovascular activity during sleep, likely impacting cardiovascular health. Aging, a primary cardiovascular risk factor, is associated with cardiac autonomic disbalance and diminished sleep slow waves. Therefore, slow waves may be linked to aging, autonomic activity and cardiovascular health. However, it
Stephanie Huwiler, M. Laura Ferster, Luzius Brogli, Reto Huber, Walter Karlen, Caroline Lustenberger   +5 more
wiley   +1 more source

Discordance Between Striatal Dopaminergic Imaging and Motor Performances in REM Sleep Behavior Disorder. [PDF]

Neurol Open Access
Zatti C, Miyagawa T, Kouchache T, Pelletier A, Lowe VJ, Criswell SR, Vernon CJ, St Louis EK, Fields JA, Gagnon JF, Kantarci K, Boeve BF, Postuma R.   +12 more
europepmc   +1 more source

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs, Caitlin E. Martin, Bernard Fuemmeler, Shanshan Chen   +3 more
wiley   +1 more source

Exploratory serum biomarker profiling in idiopathic REM sleep behavior disorder: evidence of early neurodegenerative signatures: a pilot study. [PDF]

Sleep Breath
Torres DM, Pereira FHQ, da Silva Viana M, Ramos MMS, Cunha EGB, de Araújo Melo LJR, Sobreira EST, Lopes FCA, Frota AF, Soares MVR, de-Almeida RT, Braga-Neto P, Macedo DS, Sobreira-Neto MA.   +13 more
europepmc   +1 more source

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng, Daniel Lorch, Nancy Hall, Margaret Moline   +3 more
wiley   +1 more source

REM Sleep Behavior Disorder as a Key Predictor of Cognitive Decline: Insights from a Narrative Review. [PDF]

Sleep Sci
Khorshidian F.
europepmc   +1 more source

Dreaming conundrum

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti, Francesca Siclari, Ivana Rosenzweig   +2 more
wiley   +1 more source