Results 41 to 50 of about 88,886 (260)

Digital Twin and Data-Driven Remaining Useful Life Prediction of Gearbox

open access: yesIEEE Access
Traditional approaches for predicting the remaining useful life (RUL) of gearboxes often face challenges in integrating physical and virtual data, leading to reduced prediction accuracy and an increased risk of system failure.
Quanbo Lu, Mei Li, Xiaojuan Huang
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Remaining Useful Life Prediction for Turbofan Engine Using SAE-TCN Model

open access: yesAerospace, 2023
Turbofan engines are known as the heart of the aircraft. The turbofan’s health state determines the aircraft’s operational status. Therefore, the equipment monitoring and maintenance of the engine is an important part of ensuring the healthy and stable ...
Xiaofeng Liu   +3 more
doaj   +1 more source

Differentially Private Federated Learning for Remaining Useful Life Prediction

open access: yesApplied Sciences
Accurate remaining useful life (RUL) prediction is essential for the safe and cost-effective operation of safety-critical systems such as electronic components and engines.
Arturs Nikulins   +7 more
doaj   +1 more source

Joint autoencoder-regressor deep neural network for remaining useful life prediction

open access: yesEngineering Science and Technology, an International Journal, 2023
Ubiquitous availability of IoT technologies allows processing of large amounts of data to improve prognostics tasks in industrial applications. One such important task of prognostics is the prediction of remaining useful life of a system from past ...
Kürşat İnce, Yakup Genc
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Attention-Based LSTM Network for Rotatory Machine Remaining Useful Life Prediction

open access: yesIEEE Access, 2020
As one of the key components in mechanical systems, rotatory machine plays a significant role in safe and stable operation. Accurate prediction of the Remaining Useful Life (RUL) of rotatory machine contributes to realization of intelligent operation and
Hao Zhang   +4 more
doaj   +1 more source

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