Results 111 to 120 of about 172,214 (308)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Cognitive Remediation [PDF]

American Journal of Psychiatry, 1994
openaire   +4 more sources

The Metrics of the DMA’s Success

European Journal of Risk Regulation
The Digital Markets Act (DMA) is a rare bird in competition policy. Indeed, it is a hybrid framework incorporating the institutional setting of a regulatory tool as well as the conduct already targeted by antitrust authorities in proceedings against ...
Giuseppe Colangelo, Alba Ribera Martínez   +1 more
doaj   +1 more source

PUBLIC PROCUREMENT IN THE LIGHT OF THE NEW LEGISLATIVE CHANGES [PDF]

Challenges of the Knowledge Society, 2017
The package of laws on public procurement and concessions of Romania which entered into force in May 2016 came with many new elements. Therefore, in this study, we aim to present the new conception of the lawmaker towards this subject. Not least, we will
Elena Emilia ȘTEFAN
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Section X, 2a - Diseases and Remedies

, 2013
Various diseases,of the aborigines, sorcery treatments and herbal remedies in all West Australian ...

core  

Merger Remedies

, 2017
Merger remedies have increased in frequency and expanded in scope, all with the purpose of permitting legitimate consolidation while preserving the premerger degree of competition in an industry.
John Kwoka
core   +1 more source

Addressing the Abuse of Monopsony Power in Labor Markets: Examining Potential Public and Civil Law Remedies and Sanctions

Yearbook of Antitrust and Regulatory Studies
Although thousands of reported cases involve allegations of firms illegally forming cartels in product markets, relatively few deal with similar allegations in labor markets.
Zofia Maria Mazur
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Contributory misconduct reductions in unfair dismissal remedies

, 2014
When an attempt to conciliate an unfair-dismissal claim fails, arbitration may be called upon to determine whether the dismissal was fair or unfair.In the event that the dismissal is deemed unfair, Australia’s federal industrial tribunal can reduce the ...
Southey, Kim
core