Results 141 to 150 of about 903,326 (341)

Addressing the Abuse of Monopsony Power in Labor Markets: Examining Potential Public and Civil Law Remedies and Sanctions

open access: yesYearbook of Antitrust and Regulatory Studies
Although thousands of reported cases involve allegations of firms illegally forming cartels in product markets, relatively few deal with similar allegations in labor markets.
Zofia Maria Mazur
doaj   +1 more source

PUBLIC PROCUREMENT IN THE LIGHT OF THE NEW LEGISLATIVE CHANGES [PDF]

open access: yesChallenges of the Knowledge Society, 2017
The package of laws on public procurement and concessions of Romania which entered into force in May 2016 came with many new elements. Therefore, in this study, we aim to present the new conception of the lawmaker towards this subject. Not least, we will
Elena Emilia ȘTEFAN
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Remedying Remediation?

open access: yes, 2019
Some twenty years after Jay David Bolter and David Grusin’s now classic Remediation: Understanding New Media (MIT Press, 1999), this theoretical introduction seeks to question and clarify the contours and stakes of remediation, and to sound the notion anew for productivity, pertinence and potential limits, moving the debates outside the strict ...
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A Critical Appraisal of Remedies in the EU Microsoft Cases [PDF]

open access: yes
We discuss and compare the remedies in the two cases antitrust cases of the European Union (EU) against Microsoft. The first EU case alleged (i) that Microsoft illegally bundled the Windows Media Player (WMP) with Windows; and (ii) that Microsoft did not
Ioannis Lianos, Nicholas Economides
core  

Policy and Practice Brief: Effect of Defaulted Student Loans on Return to Work Efforts [PDF]

open access: yes, 2003
This brief describes types of student loans that exist and effects or defaulted student loans on individuals benefits. Reviewed are increased efforts to collect on defaulted student loans as well as remedies to take a loan out of ...
Cebula, Ray, Hager, Ronald M
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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