Results 151 to 160 of about 903,326 (341)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Strategic Planning in the Pharmaceutical Industry: The Pivotal Role of Medical Affairs
Journal of Pharmacoeconomics and Pharmaceutical ManagementThe pharmaceutical market is both complex and diverse. It differs from country to country, even region to region and it is constantly evolving. India’s pharmaceutical sector ranks among the largest and most advanced science-based industries within ...
Abhijit Trailokya
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Se vogliamo che tutto rimanga com'è, bisogna che tutto deva essere scritto in inglese [PDF]
, 2012 The knowledge of foreign professional literature which is not written in English language is rare in the habit of American library science, and it is easily recognizable if we consider the citations of works not written in English.
Bade, David
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Histoire, Médecine et SantéThis article analyses a manuscript collection of recipes (ca. 1590-1643) and its context of production and use: the Oratory of Santa Maria in Vallicella in Rome.
Stefano Tomassetti
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Public procurement and access to justice: a legal and empirical study of the UK system [PDF]
, 2016 This article presents the findings of an empirical study into suppliers’ behaviour in enforcing EU public procurement law in the UK - where there is a low level of procurement litigation – and the factors influencing this.
Arrowsmith, Sue, Craven, Richard
core +1 more source