Results 151 to 160 of about 89,423 (306)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Novel attributes of HIV-1 elite controllers: redefining persistent HIV-1 remission. [PDF]

Curr Opin HIV AIDS
Ruiz-Mateos E.
europepmc   +1 more source

Spontanous Remission of PAN

Open Journal of Gastroenterology, 2023
Arowa Abdelgadir, Srinivasa Elamanchi
openaire   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Sustained Complete Remission After a Single Cycle of R-CHOP in Extranodal Diffuse Large B-Cell Lymphoma of the Mandible: A Case Report. [PDF]

Cureus
Furlan Silva Fabri R, Patel S, De Melo Rodrigues RM, Gomez J.   +3 more
europepmc   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, EarlyView.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Unprovoked Venous Thromboembolism in a Patient with a Small PNH Clone: A Therapeutic Dilemma. [PDF]

J Brown Hosp Med
Balusu K, Malipeddi D, Phatak P.
europepmc   +1 more source

Cutaneous and mucosal manifestations associated with celiac disease [PDF]

, 2018
Beteta Gorriti, Valia Patricia, Dios Velázquez, Álvaro de, Gómez de Castro, Celia, Palacios García, Laura, Rodrigo Sáez, Luis Ricardo, Santos-Juanes Jiménez, Jorge, Álvarez, Nuria   +6 more
core   +2 more sources

Sensitivity of flower trade‐wind cloud organisation to mesoscale atmospheric heterogeneities

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Trade‐wind cloud organisation is insensitive to dynamical and thermal heterogeneities but very sensitive to humidity mesoscale heterogeneities, especially in the cloud layer, where they form moist patches, and not in the sub‐cloud layer. Clouds and rain develop in moist patches, then cold pools develop progressively, initiating mesoscale circulations ...
Thibaut Dauhut, Fleur Couvreux, Dominique Bouniol   +2 more
wiley   +1 more source