Results 181 to 190 of about 90,197 (309)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

open access: yesAndrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino   +5 more
wiley   +1 more source

Successful treatment of refractory erosive lichen planus with abrocitinib: A case report. [PDF]

open access: yesSAGE Open Med Case Rep
Hladky V   +4 more
europepmc   +1 more source

Agroecology and Transformative Adaptation to Climate Change

open access: yesAsia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source

Networks of securitisation in the academy: The role of friendship, solidarity and radical geographies

open access: yesArea, EarlyView.
Abstract This intervention has three aims: (1) to consider how solidarities are being policed in the academy; (2) how friendships and solidarities emerge in practices of resistance; and (3) what a radical geography which embraces a decolonial pedagogy can offer us in these unsettling times.
Shereen Fernandez
wiley   +1 more source

Ethical Expertise Before and After Medically Assisted Dying: The Informal and Formal Role of the Ethicist in the Netherlands

open access: yesBioethics, EarlyView.
ABSTRACT Although we have a long‐standing and well‐institutionalized practice of medical aid in dying (MAID) in the Netherlands, it is insufficiently clarified which goals ethicists should pursue in the context of assisted dying, and which competencies they need to fulfil their role(s). We sought to contribute to this clarification.
Eva Asscher, Suzanne Metselaar
wiley   +1 more source

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