Results 201 to 210 of about 492,944 (298)

Inflammation-Masked Sporadic Colorectal Cancer Detected After Remission Induction in Elderly-Onset Ulcerative Colitis. [PDF]

ACG Case Rep J
Tanaka T, Yoshifuku Y, Teshima H, Konishi H, Zaitsu J, Nakata K, Otabe N, Mori T, Nonaka M, Fujimoto Y.   +9 more
europepmc   +1 more source

Final Analysis of the BRUIN Phase 1/2 Study Assessing the Safety and Efficacy of Pirtobrutinib Monotherapy in Patients With MCL

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib, a highly selective, non‐covalent Bruton tyrosine kinase inhibitor (BTKi) previously demonstrated durable efficacy and tolerable safety following covalent (c) BTKi therapy in heavily pretreated relapsed/refractory (R/R) mantle cell lymphoma (MCL).
Michael L. Wang, Jonathon B. Cohen, Nirav N. Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Y. Cheah, Chaitra S. Ujjani, Youngil Koh, Won Seog Kim, Sunita D. Nasta, Ian Flinn, Benoit Tessoulin, Shuo Ma, Alvaro J. Alencar, David J. Lewis, Jennifer A. Woyach, Kami J. Maddocks, Krish Patel, Yucai Wang, Joanna M. Rhodes, Constantine S. Tam, John F. Seymour, Hirokazu Nagai, Julie M. Vose, Bita Fakhri, Marc S. Hoffmann, Francisco Hernandez‐Ilizaliturri, Andrew D. Zelenetz, Anita Kumar, Talha Munir, Donald E. Tsai, Paolo Abada, Minna Balbas, Jian Li, Denise Wang, Lindsey E. Roeker, Toby A. Eyre   +36 more
wiley   +1 more source

Prognostic Impact of FLT3‐ITD Allelic Ratio in AML Patients Treated With High‐Dose Anthracycline and a FLT3 Inhibitor

American Journal of Hematology, EarlyView.
ABSTRACT The prognostic value of FLT3 internal tandem duplication (FLT3‐ITD) in acute myeloid leukemia (AML) has traditionally been stratified according to the ITD/wild‐type allelic ratio (AR) and NPM1 co‐mutation status. We evaluated the prognostic impact of FLT3‐ITD AR in 459 newly diagnosed AML patients younger than 60 years enrolled in the ...
Mathieu Leclerc, Etienne Audureau, Nicolas Duployez, Mathilde Hunault, Emmanuelle Tavernier, Cécile Pautas, Sarah Bertoli, Emmanuel Raffoux, Marie‐Anne Hospital, Tony Marchand, Maël Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria‐Pilar Gallego‐Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli‐Lebras, Ariane Mineur, Claude Gardin, Jean‐Valère Malfuson, Thomas Cluzeau, Norbert Vey, Régis Peffault de Latour, Lucie Rigolot, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean‐François Hamel, Stéphane de Botton, Arnaud Pigneux, Hervé Dombret, Claude Preudhomme, Christian Recher, Pierre‐Yves Dumas   +43 more
wiley   +1 more source

Early mepolizumab initiation during remission induction is associated with lower organ damage burden in EGPA: a multicentre cohort study. [PDF]

Rheumatology (Oxford)
Maruyama A, Ono N, Kai T, Kimoto Y, Nakano M, Inoue Y, Ueda N, Miyamura T, Otsuka K, Shinkawa Y, Tada Y, Akahoshi M, Niiro H.   +12 more
europepmc   +1 more source

Characteristics Associated With Persistent Long COVID Symptoms in Healthcare Personnel Infected With SARS‐CoV‐2 Between August 2022 and May 2024: A Multicenter Cohort Analysis of US Healthcare Personnel

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz, Amanda K. Irish, Lilly C. Lee, Howard A. Smithline, Ian D. Plumb, Melissa Briggs‐Hagen, Alexandra F. Rollins, Karisa K. Harland, Anusha Krishnadasan, Karin F. Hoth, Eliezer Santos‐León, David A. Talan, Nicholas M. Mohr, Project PREVENT Network   +13 more
wiley   +1 more source

Ex vivo JAK and TNF inhibitor-modulated immune signatures guide first-line therapy selection in rheumatoid arthritis. [PDF]

Biomark Res
Corrales S, Pérez-Sánchez C, Cerdó T, Merlo C, Malvar-Fernández B, García S, Muñoz-Barrera L, Sanchez-Pareja I, Formanti L, Moreno-Caño E, Ortega-Castro R, Calvo J, Aranda-Varela C, Ladehesa L, Font P, Abalos-Aguilera MC, Ruiz-Vilchez D, Aguirre MÁ, Barbarroja N, Alarcon-Riquelme ME, Escudero-Contreras A, López-Pedrera C.   +21 more
europepmc   +1 more source

Construction Trade Work Is Associated With Accelerated Decline in Kidney Function

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Construction workers are exposed to airborne particulates, organic solvents, and metals—agents linked to elevated risk of chronic kidney disease (CKD). Few studies have evaluated whether construction trade work is associated with longitudinal changes in estimated glomerular filtration rate (eGFR), a key indicator of kidney function.
Sammy Almashat, John M. Dement, Marianne Cloeren, Knut Ringen, Miles Fisher, Richard Rinehart   +5 more
wiley   +1 more source

First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes. [PDF]

Rheumatology (Oxford)
Russell MD, Chan CJ, Sasitharan A, Allen V, Gibson M, Adas MA, Goodliffe S, Bechman K, Cope AP, Norton S, Bosworth A, Foxton P, Price E, Sharrack S, Dass S, Emery P, Kay L, Lanyon P, Galloway JB.   +18 more
europepmc   +1 more source

Intensive treatment of persistent microalbuminuria: determinants of treatment resistance

Open Medicine, 2013
Robles Nicolas, Velasco Joaquin, Mena Candido, Angulo Enrique   +3 more
doaj   +1 more source