Results 231 to 240 of about 922,637 (337)

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao   +14 more
wiley   +1 more source

Highly Sensitive and Temperature‐Insensitive Stretchable Strain Sensor with Microcrack‐Engineered Architecture

open access: yesAdvanced Science, EarlyView.
This study proposes a stretchable strain sensor that demonstrates a high gauge factor of 2.3 × 104 and excellent linearity (R2 = 0.98), while maintaining temperature insensitivity under applied strain. This performance is achieved through a microcrack architecture formed by stacking a brittle, low‐resistance material with a stretchable, high‐resistance
Yu Kato   +4 more
wiley   +1 more source

Efficacy of mirikizumab induction therapy in inflammatory bowel disease: A systematic review and meta-analysis. [PDF]

open access: yesMedicine (Baltimore)
Khan SA   +8 more
europepmc   +1 more source

Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis.

open access: yesGastroenterology, 2014
W. Sandborn   +14 more
semanticscholar   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia: Time to Move Toward a Minimal Residual Disease-Based Definition of Complete Remission?

open access: yesJournal of Clinical Oncology, 2016
D. Araki   +9 more
semanticscholar   +1 more source

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