Results 231 to 240 of about 492,944 (298)

Divergent effects of interleukin-6 and ghrelin on remission and relapse in depression treatment. [PDF]

Int J Neuropsychopharmacol
Kim JM, Kang HJ, Kim JW, Jhon M, Lee JY, Kim SW, Shin IS.   +6 more
europepmc   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

Angewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa Ponomareva, Isaline Fagon, Leslie Fève, Kendall Paige, Courtney L. Brown, Nora Schwartz, Jacob Hecht, Jennifer Nguyen, Jon S. Thorson, Jacques Neefjes, S. Eric Nybo, Khaled A. Shaaban, Mikko Metsä‐Ketelä   +15 more
wiley   +1 more source

Post-transplant BRAF/MEK inhibitor maintenance sustains complete remission in BRAF V600E-mutant histiocytic sarcoma. [PDF]

Ann Hematol
Karim I, Arnold T, Bräuninger A, Dohse M, Schell F, Samra MA, Tarawneh T, Burchert A, Gattenlöhner S, Sohlbach K.   +9 more
europepmc   +1 more source

Fecal Virome Transplantation in Human Disease and Livestock Production: Evidence, Mechanisms, and Translational Challenges

Animal Research and One Health, EarlyView.
Fecal virome transplantation may reshape bacterial communities and host responses while reducing viable bacterial transfer. Preclinical evidence suggests biological activity, but human efficacy remains uncertain, and translation requires product standardization, causal validation, donor–recipient matching, and rigorous biosafety assessment.
Luanyang Shi, Yongjuan Guan, Guanxiang Liang   +2 more
wiley   +1 more source

Achieving clinical remission in moderate-to-severe asthma using inhaled triple therapy. [PDF]

ERJ Open Res
Canonica GW, Singh D, Papi A, Brusselle G, Piraino A, Franzini L, Vele A, Hernandez G, Skloot G, Virchow JC.   +9 more
europepmc   +1 more source