Results 181 to 190 of about 1,471,327 (421)

Randomized clinical trial of cystosine arabinoside and 6-thioguanine in remission induction and consolidation of adult nonlymphocytic acute leukemia [PDF]

, 1977
Jerry P. Lewis, James W. Linman, G. June Marshall, Thomas F. Pajak, Joseph R. Bateman   +4 more
openalex   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Sequential cyclophosphamide and doxorubicin for induction of complete remission in children with disseminated neuroblastoma [PDF]

, 1981
Alexander A. Green, F. Ann Hayes, H. Omar Hustu   +2 more
openalex   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Rapid induction of remission in large vessel vasculitis by IL-6 blockade

Swiss Medical Weekly, 2011
OBJECTIVE: To evaluate the effect of IL-6 blockade using tocilizumab in inducing remission of arterial large vessel vasculitides (LVV). METHODS: Five consecutive patients with giant-cell arteritis (GCA) and two with Takayasu’s arteritis ...
MN Seitz, S Reichenbach, HM Bonel, S Adler, F Wermelinger, PM Villiger   +5 more
doaj   +1 more source

A Logic for Non-Monotone Inductive Definitions [PDF]

arXiv, 2005
Well-known principles of induction include monotone induction and different sorts of non-monotone induction such as inflationary induction, induction over well-founded sets and iterated induction. In this work, we define a logic formalizing induction over well-founded sets and monotone and iterated induction. Just as the principle of positive induction
arxiv  

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

A Randomized Controlled Trial Comparing Remission Induction with Modified Multitarget Therapy with Intravenous Cyclophosphamide in Proliferative Lupus Nephritis. [PDF]

Indian J Nephrol, 2023
Pal A, Chaudhury AR, Bhunia A, Bhattacharya K, Chatterjee S, Divyaveer SS, Sircar D, Sen D.   +7 more
europepmc   +1 more source

Jailbreaking as a Reward Misspecification Problem [PDF]

arXiv
The widespread adoption of large language models (LLMs) has raised concerns about their safety and reliability, particularly regarding their vulnerability to adversarial attacks. In this paper, we propose a novel perspective that attributes this vulnerability to reward misspecification during the alignment process. This misspecification occurs when the
arxiv  

Cyclic and Inductive Calculi are equivalent [PDF]

arXiv, 2011
Brotherston and Simpson [citation] have formalized and investigated cyclic reasoning, reaching the important conclusion that it is at least as powerful as inductive reasoning (specifically, they showed that each inductive proof can be translated into a cyclic proof). We add to their investigation by proving the converse of this result, namely that each
arxiv