Results 211 to 220 of about 158,388 (335)

Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial [PDF]

open access: green, 2011
Walter Reinisch   +12 more
openalex   +1 more source

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu   +7 more
wiley   +1 more source

The prophylactic use of granulocyte-colony stimulating factor during remission induction is associated with increased leukaemia-free survival of adults with acute lymphoblastic leukaemia: A joint analysis of five randomised trials on behalf of the EWALL [PDF]

open access: bronze, 2011
Sebastian Giebel   +10 more
openalex   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

open access: yesAdvanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen   +7 more
wiley   +1 more source

Matching-adjusted indirect comparisons of efficacy outcomes between etrasimod and ozanimod for moderately to severely active ulcerative colitis

open access: yesJournal of Comparative Effectiveness Research
Aim: Etrasimod and ozanimod are selective sphingosine 1-phosphate receptor modulators targeting the S1P1,4,5, and S1P1,5 receptors, respectively, for the treatment of patients with moderately to severely active ulcerative colitis (UC).
Vipul Jairath   +8 more
doaj   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

open access: yesAdvanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu   +7 more
wiley   +1 more source

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