Results 31 to 40 of about 12,017 (266)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

RS-Mamba for Large Remote Sensing Image Dense Prediction

IEEE Transactions on Geoscience and Remote Sensing
Context modeling is critical for remote sensing image dense prediction tasks. Nowadays, the growing size of very-high-resolution (VHR) remote sensing images poses challenges in effectively modeling context. While transformer-based models possess global modeling capabilities, they encounter computational challenges when applied to large VHR images due ...
Sijie Zhao, Hao Chen 0045, Xueliang Zhang 0002, Pengfeng Xiao, Lei Bai 0001, Wanli Ouyang   +5 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

RS-LLaVA: A Large Vision-Language Model for Joint Captioning and Question Answering in Remote Sensing Imagery [PDF]

In this paper, we delve into the innovative application of large language models (LLMs) and their extension, large vision-language models (LVLMs), in the field of remote sensing (RS) image analysis. We particularly emphasize their multi-tasking potential
Laila Bashmal, Riccardo Ricci, Mohamad Mahmoud Al Rahhal, Yakoub Bazi, Farid Melgani   +4 more
core   +1 more source

Large-Scale Remote Sensing Image Retrieval Based on Semi-Supervised Adversarial Hashing [PDF]

, 2019
Remote sensing image retrieval (RSIR), a superior content organization technique, plays an important role in the remote sensing (RS) community. With the number of RS images increases explosively, not only the retrieval precision but also the retrieval ...
Fang Liu, Chao Liu, Licheng Jiao, Xu Tang, Xiangrong Zhang, Jingjing Ma   +5 more
core   +1 more source

A Novel Shipyard Production State Monitoring Method Based on Satellite Remote Sensing Images [PDF]

, 2023
Monitoring the shipyard production state is of great significance to shipbuilding industry development and coastal resource utilization. In this article, it is the first time that satellite remote sensing (RS) data is utilized to monitor the shipyard ...
Yuhong Tu, Yan Song, Haitian Zhu, Xinli Yu, Wanrou Qin   +4 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Combining KAN with CNN: KonvNeXt’s Performance in Remote Sensing and Patent Insights [PDF]

Rapid advancements in satellite technology have led to a significant increase in high-resolution remote sensing (RS) images, necessitating the use of advanced processing methods.
Minjong Cheon, Changbae Mun
core   +1 more source

Improved Deep Learning-Based Vehicle Detection for Urban Applications Using Remote Sensing Imagery [PDF]

, 2023
Remote sensing (RS) data can be attained from different sources, such as drones, satellites, aerial platforms, or street-level cameras. Each source has its own characteristics, including the spectral bands, spatial resolution, and temporal coverage ...
Hesham A. Abdushkour, Alaa O. Khadidos, Khaled H. Alyoubi, Abdulrhman M. Alshareef, Adil O. Khadidos, Mahmoud Ragab   +5 more
core   +1 more source

Influence of Geometric Design on Mechanical Performance of Auxetic Metastructure

Advanced Engineering Materials, EarlyView.
Strategic geometric reinforcement transforms auxetic performance. This study evaluates 3D‐printed arrowhead metastructures, revealing that a modified design with local ring reinforcement suppresses premature failure to achieve superior energy absorption and structural efficiency.
Muhammad Gulzari, Supharoek Sornsomrit, Muhammad Ayaz Akbar, Stephan Rudykh   +3 more
wiley   +1 more source