Results 141 to 150 of about 70,563 (302)
Study of removing ability of removers for paint systems removal
«Aviation Materials and Technologies», 2017 L.V. Semenova +2 more
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
inical case describes the treatment of a patient with an Angle class III malocclusion using an removable partial overdenture (RPOD). This treatment was selected as it was minimally invasive, had relatively low laboratory costs and was a simple technique.
Vinícius Carvalho Porto, Rodolfo Azevedo Branco Kazniakowski, Fernando Ribas Baggio, Paulo César Rodrigues Conti
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Development and Validation of a Patient-Reported Outcome Questionnaire for Children Undergoing Removable Orthodontic Treatment. [PDF]
Dent J (Basel)Tinela P +8 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Implant-Assisted Removable Partial Dentures with Surveyed Crowns: A Narrative Review of Treatment Concepts, Material Considerations, and Clinical Outcomes. [PDF]
Dent J (Basel)Phusadeekunpaisan I +2 more
europepmc +1 more source