Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Comparative impact of clear aligners versus fixed orthodontic appliances on periodontal health, pain, and quality of life: a systematic review and meta-analysis. [PDF]
Kaur K +4 more
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Peripheral Giant Cell Granuloma Associated With an Impacted Tooth and Prosthetic Irritation: A Multifactorial Etiological Insight and Surgical Management Challenge. [PDF]
Farouk M, Bentahar O.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
The study of prosthetic needs and oral health challenges of aging population. [PDF]
Kamiyeva N, Rizabekova Z, Saliev T.
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Dental Management of Tatton-Brown-Rahman Syndrome: A Case Report. [PDF]
Ghulman RR +4 more
europepmc +1 more source
Functional and aesthetic oral rehabilitation after cancer treatment using dental prosthesis and hyaluronic acid injections: A case report and review of literature. [PDF]
Hessloehl N +3 more
europepmc +1 more source
Patient perceptions of prosthodontic management options for partially dentate older adults: a qualitative study. [PDF]
Meaney S +8 more
europepmc +1 more source

