Results 201 to 210 of about 2,124,411 (292)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Synergistic elimination of antibiotic resistance genes and tetracycline antibiotics in wastewater <i>via</i> a Z-scheme Bi<sub>2</sub>WO<sub>6</sub>/g-C<sub>3</sub>N<sub>4</sub> heterojunction: degradation pathways and mechanism. [PDF]
Liu Y, Sun G, Cao Y, Li X, Li Z, Chen Z.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Humic Acid-Stabilized Biogenic FeS Nanoparticles for Cr(VI) Removal Under Simulated Acidic Mine Drainage Conditions: Optimization and Interfacial Transformation Pathways. [PDF]
Dai M, Di J, Zhang M.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Enamel Integrity and Residual Composite Following Clear Aligner Attachment Removal: A Systematic Review. [PDF]
Nassar N +5 more
europepmc +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Isolation of aerobic denitrifying bacteria Stutzerimonas stutzeri and its application in coking wastewater treatment. [PDF]
Naseer K +7 more
europepmc +1 more source

