Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Possibility of using plasma-processed hybrid nanofibers to remove toluene in air stream
Introduction: Despite nanofibers have attracted great interests for filtering particulate matters from the air stream, fewer studies have been done on the feasibility of their use in the removal of gas pollutants, while the both pollutants are present in
Somayeh Farhang Dehghan +3 more
doaj
Carbon and nitrogen dynamics: Greenhouse gases in groundwater beneath a constructed wetland treating municipal wastewater [PDF]
Conference oral presentationConstructed wetlands (CW) act as nitrogen (N) sinks and reactors facilitating a number of physical, chemical and biological processes.
Carroll, Paul +5 more
core
Removal of Arsenic (III) from groundwater applying a reusable Mg-Fe-Cl layered double hydroxide [PDF]
BACKGROUND: Layered double hydroxide compounds (LDHs) have been applied for the removal of oxyanions including arsenate (As(V)). However, the aim of this present research is to develop a LDH to treat arsenite (As(III)).
Ashekuzzaman , S.M. +5 more
core +3 more sources
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Study of Pre-ozonation effects on Physicochemical and Biological Properties of Drinking Water
Background and objectives:Pre-ozonation in water treatment is used for various purposes such as; improving the coagulation process, reducing the production of trihalomethanes, color removal, removal of iron and manganese, control of microorganisms, and ...
Bahman Masoomi
doaj
Fine and ultrafine particle removal efficiency of new residential HVAC filters.
Particle air filters used in central residential forced-air systems are most commonly evaluated for their size-resolved removal efficiency for particles 0.3-10 µm using laboratory tests. Little information exists on the removal efficiency of commercially
Torkan Fazli +2 more
semanticscholar +1 more source
Performance of silica-supported copper oxide sorbents for SOx/NOx-removal from flue gas II. Selective catalytic reduction of nitric oxide by ammonia [PDF]
The selective catalytic reduction (SCR) of nitric oxide by ammonia was studied for silica-supported copper oxide particles to be used as a sorbent/catalyst in a continuous process for the simultaneous removal of SOx and NOx from flue gases.
Edelaar, A.C.S. +4 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Opuntia ficus-indica (OFI) is a high added value species which different organs are used in several fields, including water purification. The present study intended to treat contaminated well water using naturally prepared coagulant from the cladodes of
Farah Abidi +6 more
doaj

