Results 131 to 140 of about 7,982,343 (363)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Heterogeneous catalytic ozonation of 2, 4-dinitrophenol in aqueous solution by magnetic carbonaceous nanocomposite: catalytic activity and mechanism [PDF]

, 2016
Herein, the catalytic properties of a carbonaceous nanocomposite in the catalytic ozonation process (COP) of 2, 4-dinitrophenol (2, 4-DNP) were investigated and the results were compared with those obtained from single ozonation process (SOP).
Bahrami Asl, F., Baneshi, M.M., Dadban Shahamat, Y., Okhovat, N., Sadeghi, M., Shahryari, A.   +5 more
core  

Effect of Anode Dielectric Coating on Hall Thruster Operation [PDF]

, 2003
An interesting phenomenon observed in the near-anode region of a Hall thruster is that the anode fall changes from positive to negative upon removal of the dielectric coating, which is produced on the anode surface during the normal course of Hall ...
Bishaev A. M., Kliarfeld B. N., L. Dorf, Melikov I. V., Morozov A. I., N. J. Fisch, V. Semenov, Y. Raitses   +7 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

An Investigation on the Treatment of Wastewater Disperse Dye by Electrocoagulation and Examine the Use of the Treated Dye for Flora and Fauna [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The removal of disperse dye from wastewater is a critical and time-consuming task along with a significant issue raised by disperse dye in the development of toxic aromatic amines.
M.S. Asath Murphy, D. Jovitha Jane, Riju S Robin, S. Sahaya Leenus, Jegathambal Palanichamy, Parameswari Kalivel   +5 more
doaj   +1 more source

Removal of Cyanides from Gadung (Dioscorea hispida Dennst.) Tuber Chips using Leaching and Steaming Techniques [PDF]

, 2011
Gadung (Dioscorea hispida Dennst.) has been considered as one of staple foods in Indonesia. However, its high cyanides content has limited its utilisation for commercial food production. This work is aimed to investigate the removal of cyanides content
Budiyati, C.S., Kumoro, A.C., Retnowati, D.S.   +2 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Machine learning using random forest to model heavy metals removal efficiency using a zeolite-embedded sheet in water [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: Zeolite has been recognized as a potential adsorbent for heavy metals in water. The form of zeolite that is generally available in powder has challenged the use of zeolite in the environment.
N.D. Takarina, N. Matsue, E. Johan, A. Adiwibowo, M.F.N.K. Rahmawati, S.A. Pramudyawardhani, T. Wukirsari   +6 more
doaj   +1 more source

One-step synthesis of Co-doped UiO-66 nanoparticle with enhanced removal efficiency of tetracycline: Simultaneous adsorption and photocatalysis

Chemical Engineering Journal, 2018
In this study, a novel recyclable Co-doped UiO-66 nanoparticle was synthesized by a one-step solvothermal method. A high adsorption capacity of 224.1 mg g−1 was obtained by the CoUiO-1 nanoparticle, then the adsorbed tetracycline (TC) molecules could be ...
Jiao Cao, Zhao-hui Yang, Weiping Xiong, Yao-yu Zhou, Peng Yanrong, Xin Li, Chengyun Zhou, Rui Xu, Yanru Zhang   +8 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source