Results 151 to 160 of about 7,982,343 (363)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
High speed machining of space shuttle external tank liquid hydrogen barrel panel [PDF]
Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported.
Hankins, J. D.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Landfill leachate treatment using free water surface constructed wetlands [PDF]
, 2007 Nowadays, solid waste management and wastewater treatment are the most important problems that we are facing. The amount of solid waste produced around the world is increasing at high rate as well as in Malaysia. Although there are different alternatives
Othman, Siti Rabe’Ah
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Journal of Health and Pollution, 2018 Background. Adsorption is a unique and promising method for the removal of trace metals from an aqueous environment using cost-effective and readily available biochars. Objective. The present study examined mono and simultaneous adsorption of cadmium (Cd)
Abudu Ballu Duwiejuah +4 more
doaj +1 more source
Intergrated leachate treatment by sequencing batch reactor (SBR) and micro-zeolite (MZ) [PDF]
, 2015 Biological treatment has a lot of potential in leachate treatment with the ability of the biodegradable substrates and this method can reduce the cost of treatment residues with respect to ecological and economical requirements.The aims of this study are
Abu Bakar, Amnani
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source