Results 51 to 60 of about 27,466 (244)

Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images

Diagnostic Pathology, 2020
Background Multiplex immunohistochemistry (mIHC) permits the labeling of six or more distinct cell types within a single histologic tissue section. The classification of each cell type requires detection of the unique colored chromogens localized to ...
Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc, Joel Saltz   +12 more
doaj   +1 more source

AI + Drawing Enhances the Efficiency of Human Anatomy Education

Clinical Anatomy, EarlyView.
ABSTRACT Human anatomy is a fundamental core course in medical education, and its teaching effectiveness directly influences students' understanding and application of medical knowledge. However, traditional anatomy instruction often faces challenges such as limited teaching resources and the high cognitive difficulty students experience.
Fangfang Zhou, Yi Yang, Jiayou Liu, Xiaohua Zhu   +3 more
wiley   +1 more source

Deep rTMS of the insula disrupts cigarette self-administration and modulates insula-centric brain function in smokers with schizophrenia

Brain Stimulation, 2021
Scott J. Moeller, Roberto Gil, Topaz Baumvoll, Kenneth Wengler, Natalka Fallon, Jodi J. Weinstein, Jared X. Van Snellenberg, Sameera Abeykoon, Greg Perlman, John Williams, Lucian Manu, Mark Slifstein, Clifford M. Cassidy, Diana M. Martinez, Anissa Abi-Dargham   +14 more
doaj   +1 more source

Dynamic Reactivity: Reversible Reaction of a Phosphinine–Borane Adduct With Water and Double Hydrophosphination

Chemistry – A European Journal, EarlyView.
A phosphinine–borane Lewis pair shows a dynamic mode of water addition, revealing reversible and regioselective transformations that expand the reactivity of aromatic phosphorus heterocycles and open pathways to stimuli‐responsive systems for catalysis, small‐molecule activation, and functional materials.
Samantha Frank, Ádám Horváth, Júlia Boglárka Horváth, Chiara Interdonato, Moritz J. Ernst, Priya Kumar, Zoltán Benkő, Christian Müller   +7 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Computer vision detects covert voluntary facial movements in unresponsive brain injury patients

Communications Medicine
Background Many brain injury patients who appear unresponsive retain subtle, purposeful motor behaviors, signaling capacity for recovery. We hypothesized that low-amplitude movements precede larger-amplitude voluntary movements detectable by clinicians ...
Xi Cheng, Sujith Swarna, Jermaine Robertson, Nathaniel A. Cleri, Jordan R. Saadon, Chiemeka Uwakwe, Yindong Hua, Seyed Morsal Mosallami Aghili, Cassie Wang, Robert S. Kleyner, Xuwen Zheng, Ariana Forohar, John Servider, Kurt Butler, Chao Chen, Jordane Dimidschstein, Petar M. Djurić, Charles B. Mikell, Sima Mofakham   +18 more
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Economically optimized design point of high-field stellarator power-plant

Nuclear Fusion
High temperature superconductors (HTSs) expand the design space of stellarator power-plants (PPs) toward high magnetic fields B , enabling compact major radii R .
Victor Prost, Francesco A. Volpe
doaj   +1 more source

Policy Spandrels: How Design Decisions Can Open Up Spaces for Unintended Policy Change

European Policy Analysis, EarlyView.
ABSTRACT This article introduces the concept of policy spandrels to make sense of public policies producing second‐order effects that are unintentional from the perspective of policy design and yet are fraught with consequences. By analogy with architectural spandrels—leftover spaces that can be used for unforeseen purposes—policy change can be enabled
Martino Maggetti
wiley   +1 more source

(Re)humanizing Blackness: Integrating BlackCrit in the Mental Health Counseling of Black Clients

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT Does Black mental health matter? Historically, mental illness in the Black community has been inadequately addressed. Yet Black Americans experience more severe psychological distress than other races, and they are also more likely to experience poor outcomes in counseling.
Demetrius Cofield
wiley   +1 more source