Results 61 to 70 of about 633,439 (288)

Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images

open access: yesDiagnostic Pathology, 2020
Background Multiplex immunohistochemistry (mIHC) permits the labeling of six or more distinct cell types within a single histologic tissue section. The classification of each cell type requires detection of the unique colored chromogens localized to ...
Danielle J. Fassler   +12 more
doaj   +1 more source

What is event led regeneration? Are we confusing terminology or will London 2012 be the first Games to truly benefit the local existing population? [PDF]

open access: yes, 2010
The term regeneration means keeping the locality available for the same social classes and improving the infrastructure for their benefit, however examination of previous games including Barcelona 1992 and Sydney 2000 has shown evidence of renaissance ...
Sadd, Deborah
core   +1 more source

Deep rTMS of the insula disrupts cigarette self-administration and modulates insula-centric brain function in smokers with schizophrenia

open access: yesBrain Stimulation, 2021
Scott J. Moeller   +14 more
doaj   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

VI. Renaissance Humanism

open access: yes, 1958
Between the end of the High Middle Ages (about 1350) and the Protestant Reformation in the sixteenth century, the character of Western Civilization was profoundly altered. Earlier chapters have already told how most institutions and values characteristic
Bloom, Robert L.   +6 more
core  

Electrochemical Dehydration of Carboxamides to Their Nitriles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Electrochemical dehydration of carboxamides to nitriles is achieved using thiocyanate‐mediated activation, avoiding stoichiometric reagents. In an undivided cell at ambient conditions, 18 aromatic and aliphatic substrates give good‐to‐excellent yields (up to 84%) with functional‐group tolerance. Cyclic voltammetry supports an EC‐type‐mediated oxidation.
Enrico Lunghi   +2 more
wiley   +1 more source

Computer vision detects covert voluntary facial movements in unresponsive brain injury patients

open access: yesCommunications Medicine
Background Many brain injury patients who appear unresponsive retain subtle, purposeful motor behaviors, signaling capacity for recovery. We hypothesized that low-amplitude movements precede larger-amplitude voluntary movements detectable by clinicians ...
Xi Cheng   +18 more
doaj   +1 more source

“Havana Reads the Harlem Renaissance: Langston Hughes, Nicolás Guillén, and the Dialectics of Transnational American Literature” [PDF]

open access: yes, 2010
This essay reconsiders a famous episode of anti-imperial modernism, Langston Hughes’ collaboration with the Afro-Cuban poet Nicolás Guillén. While the episode is often remembered in American literary history as an instance of the more famous Hughes ...
John Patrick Leary
core   +1 more source

Policy Spandrels: How Design Decisions Can Open Up Spaces for Unintended Policy Change

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT This article introduces the concept of policy spandrels to make sense of public policies producing second‐order effects that are unintentional from the perspective of policy design and yet are fraught with consequences. By analogy with architectural spandrels—leftover spaces that can be used for unforeseen purposes—policy change can be enabled
Martino Maggetti
wiley   +1 more source

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